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BioWorld Science

Aug. 13, 2019

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Phosphorylation of DLC1 by SRC and ERK decreases its tumor suppressor functions

1,18-Octodecanedioc acid conjugated to paclitaxel is active in complex with human serum albumin

Novel variants in WDR37 gene underlie a new syndromic neurological disorder

New MEK inhibitor URML-3881 potentiates cisplatin efficacy in CCOC

Good news, bad news macrophages identified in arthritis

MAbs can be smuggled past BBB

Interim data reported from phase I study of DS-Cav1 vaccine

Xiangbei Welman Pharmaceutical describes compounds for gout, hyperuricemia

Shanghai Yingli Pharmaceutical patents TGFR-1 inhibitors

Mu-opioid receptor agonists discovered at Sichuan Kelun-Biotech Biopharmaceutical

Inhibition of mitoNEET shows antileukemic activity in drug-resistant cells and in vivo models

FDA grants accelerated approval for bedaquiline in adolescents with MDR-TB

PALM Ebola study stopped early due to favorable results for two of four candidates

TR-FRET-based screening identifies novel CBP bromodomain inhibitor with therapeutic potential

Oncologie and Merck & Co. to test bavituximab plus Keytruda in gastric cancer

Basilea initiates phase I/II FIDES-02 study of derazantinib in urothelial cancer

Study finds best tools for pinpointing genetic disease drivers

Interim data from phase Ib study of KPL-716 supports phase II development

Deciphera Pharmaceuticals presents new clinical data for ripretinib in patients with GIST

Positive interim data presented from first in human study of TERN-201 in NASH