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BioWorld Science

Sep. 16, 2019

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Gorilla virus makes stealth vaccine vector

Results from first clinical study evaluating KB-195 in patients with urea cycle disorders

Akouos reveals lead program for sensorineural hearing loss

Armata developing AP-PA02 targeting P. aeruginosa to treat respiratory infections

A silica cage ensures thermal stability of tuberculosis vaccine candidates without refrigeration

Eisai and Biogen decide to discontinue phase III MISSION AD program of elenbecestat

Recruitment ongoing in phase I study of DFP-14927

Replimune and Regeneron initiate phase II study of cemiplimab in cutaneous squamous cell carcinoma

Mutations in the PTCD3 gene identified as a novel cause of Leigh syndrome

Design of novel zebrafish models of cystinosis

Siponimod shows efficacy in combined toxic and inflammatory animal model of multiple sclerosis

NTP-42 alone and combined with sildenafil alleviates experimental pulmonary arterial hypertension

New biomarkers for NSCLC identified

Interrupting obesity-associated breast cancer progression

Incyte divulges new MAP4K1 inhibitors

New genes linked to mitral valve prolapse

Ono Pharmaceutical patents lysophospholipid S1P5 receptor agonists

ChemoCentryx synthesizes new PD-1/PD-L1 interaction inhibitors

Universita di Pisa identifies SIRT1 activators

FDA clears initiation of phase I trial of oral foralumab

Southern Research Institute discovers NF-kappaB activators

FDA and EMA offer Auris Medical guidance on phase II/III trial with Keyzilen

Phase III CANDOR study of daratumumab in multiple myeloma meets primary endpoint

Oncotartis conducts first-in-human study of OT-82 in relapsed or refractory lymphoma

Bayer launches first-in-human study of BAY-2416964 in advanced cancer

Model of sleep-disordered breathing may clarify associated disorders

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