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BioWorld Science

Oct. 4, 2019

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Targeting ATP6V1A subunit in the v-ATPase complex inhibits mTORC1 signaling and activates autophagy

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Allogene Therapeutics initiates phase I study of ALLO-715

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FDA approves Entresto for pediatric heart failure

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AL-008 potentiates the antitumor effector functions of macrophages and dendritic cells

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TERT gene fusions as novel biomarkers in metastatic Leydig cell tumors

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Phase I safety and PK data presented for novel CXCR4 antagonist YF-H-2015005

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Black Diamond Therapeutics describes preclinical activity of mutant EGFR/HER2 inhibitor BDTX-189

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Universita degli Studi di Siena discovers new antivirals

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New arginase inhibitors identified at Merck & Co.

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Ethris and Munster University Hospital receive support for work in primary ciliary dyskinesia

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Voronoi patents EGFR/JAK3 inhibitors

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Free fatty acid receptor 4 agonists disclosed by Axxam

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PARAGON-HF results for sacubitril/valsartan in heart failure with preserved ejection fraction

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Liver-targeted uncouplers reverse type 2 diabetes, fatty liver in primates

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FDA approves Descovy for HIV-1 PrEP

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Arbutus discontinues development of AB-506 following cases of acute hepatitis

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Healx collaborates with ICR to discover treatments for diffuse intrinsic pontine glioma

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Prometheus Biosciences and Takeda collaborate to develop novel IBD therapies

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Deinove studies DNV-3837 in phase II for C. difficile infection

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