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BioWorld - Tuesday, April 23, 2024
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BioWorld Science
Nov. 13, 2019
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Role of p300 in BRD4-NUT-driven NUT carcinomas and novel dual BET/p300 bromodomain inhibitors
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MAb targeting TREM1+ myeloid cells boosts antitumor immunity and checkpoint inhibitor sensitivity
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Prelude initiates phase I study of PRT-811 in advanced solid tumors, gliomas and myelofibrosis
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Encouraging results seen in phase II studies of NanoPac paclitaxel
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Corcept initiates phase II study of miricorilant for antipsychotic-induced weight gain
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Small-molecule STING agonist promotes durable antitumor immunity causing complete tumor regression
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Case study points to protective AD gene
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RNA controls muscle stem cells
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24-week data presented from HMM0301 phase III monotherapy study of dorzagliatin
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FDA approves IND for WP-1066
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FDA places on hold the phase I/II IGNITE DMD study of SGT-001
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New data presented for ParvOryx in human ovarian cancer explants
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DCC-3116 as a promising inhibitor of autophagy in preclinical models of RAS-mutant cancers
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Preclinical and preliminary first-in-human data presented for STRO-002
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Chugai Pharmaceuticals presents phase I data for EOS-789
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SentiBio presents novel allogenic cell therapy, SENTI-101
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KD-025 meets primary endpoint at interim analysis of pivotal ROCKstar study in chronic GvHD
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Positive data presented from initial cohort of phase IIb study of ORMD-0801 in T2D
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Virginia Tech Intellectual Properties describes mitochondrial uncouplers
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Celgene patents compounds for diffuse large B-cell lymphoma
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Macrocyclic oligopeptides identified at Roche
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Vertex, Merck & Co. describe endoplasmic reticulum stress inducers
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New P2X7 receptor antagonists identified at Shionogi
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Break out the sparkling apple cider for DUR-928 alcoholic hepatitis data
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New exploratory phase I/II study in Japan assesses NS-089 in Duchenne muscular dystrophy
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Bellerophon reports initial data from acute hemodynamic study of INOpulse
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