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BioWorld - Wednesday, December 31, 2025
Home » Newsletters » BioWorld Science

BioWorld Science

Nov. 15, 2019

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Radiosensitivity can be restored in advanced cancers

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New systemic bioluminescent cell line xenograft models for drug discovery in hematologic cancers

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Inhibition of fatty acid synthase with FT-4101 reduces hepatic de novo lipogenesis in healthy adults

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Merck & Co.'s MK-5890 shows acceptable safety profile and early antitumor activity

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Aged gut microbiota transplants show benefits in young mice

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Nouscom initiates phase I study of NOUS-209 in microsatellite unstable solid tumors

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Sansheng's clinical trial application for HIF-117 capsules cleared in China

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Arthrosi Therapeutics presents preclinical and phase I results for AR-882

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Cerveau Technologies starts Japanese phase I study of [18F]MK-6240

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First patient dosed in phase Ib/IIa proof-of-concept study of BRII-179

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Hoth Therapeutics initiates preclinical testing of topical aprepitant

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Gilead presents phase II results for selgantolimod in patients with chronic HBV

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Preliminary phase I/II data for BMS-986148 monotherapy and combination with nivolumab

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Preclinical data suggest MCLA-129 has potential for NSCLC resistant to EGFR-targeted therapies

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Janssen describes compounds for respiratory syncytial virus infections

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ViiV Healthcare synthesizes prodrugs of HIV maturation inhibitors

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New mu-opioid receptor agonists identified at Sichuan Kelun-Biotech Biopharmaceutical

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Pfizer patents cyclin-dependent kinase inhibitors

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New IDO-1 inhibitors identified at Phenex Discovery Verwaltungs

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Results from SILK cohort evaluating tesevatinib in ADPKD patients presented at Kidney Week

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Phase II study of AV-101 in major depressive disorder does not meet primary endpoint

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I-Mab obtains Chinese IND clearance for phase I trials of TJM-2 in rheumatoid arthritis

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FDA approves Fetroja for complicated urinary tract infections

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FDA grants accelerated approval to Brukinsa for mantle cell lymphoma

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Interim data presented from phase I study of TK-216 in Ewing's sarcoma

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resTORbio stops development of RTB-101 for clinically symptomatic respiratory illness

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