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BioWorld Science

Nov. 15, 2019

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Radiosensitivity can be restored in advanced cancers

New systemic bioluminescent cell line xenograft models for drug discovery in hematologic cancers

Inhibition of fatty acid synthase with FT-4101 reduces hepatic de novo lipogenesis in healthy adults

Merck & Co.'s MK-5890 shows acceptable safety profile and early antitumor activity

Aged gut microbiota transplants show benefits in young mice

Nouscom initiates phase I study of NOUS-209 in microsatellite unstable solid tumors

Sansheng's clinical trial application for HIF-117 capsules cleared in China

Arthrosi Therapeutics presents preclinical and phase I results for AR-882

Cerveau Technologies starts Japanese phase I study of [18F]MK-6240

First patient dosed in phase Ib/IIa proof-of-concept study of BRII-179

Hoth Therapeutics initiates preclinical testing of topical aprepitant

Gilead presents phase II results for selgantolimod in patients with chronic HBV

Preliminary phase I/II data for BMS-986148 monotherapy and combination with nivolumab

Preclinical data suggest MCLA-129 has potential for NSCLC resistant to EGFR-targeted therapies

Janssen describes compounds for respiratory syncytial virus infections

ViiV Healthcare synthesizes prodrugs of HIV maturation inhibitors

New mu-opioid receptor agonists identified at Sichuan Kelun-Biotech Biopharmaceutical

Pfizer patents cyclin-dependent kinase inhibitors

New IDO-1 inhibitors identified at Phenex Discovery Verwaltungs

Results from SILK cohort evaluating tesevatinib in ADPKD patients presented at Kidney Week

Phase II study of AV-101 in major depressive disorder does not meet primary endpoint

I-Mab obtains Chinese IND clearance for phase I trials of TJM-2 in rheumatoid arthritis

FDA approves Fetroja for complicated urinary tract infections

FDA grants accelerated approval to Brukinsa for mantle cell lymphoma

Interim data presented from phase I study of TK-216 in Ewing's sarcoma

resTORbio stops development of RTB-101 for clinically symptomatic respiratory illness

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