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BioWorld Science

Dec. 2, 2019

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World AIDS Day: Immediate ART initiation for neonates with HIV-1 provides significant benefits

New selective and potent mTOR inhibitor discovered through structure-based drug design

Evaluation of neuronal responses to La Crosse virus infection in human cerebral organoids

Chidamide approved in China for breast cancer indication

Takeda presents 18-month data from pivotal phase III TIDES study of TAK-003 dengue vaccine

Apatinib demonstrates safety and efficacy in phase II study in adenocarcinoma of the head and neck

Roche publishes data from iMATRIX study of atezolizumab

MiR-125b as a novel target in diabetes

Avidin describes new apoptosis inducers

Shenzhen Salubris Pharmaceuticals identifies new PAR-4 antagonists

Beijing Innocare Pharmaceutical Technology patents VEGFR inhibitors

New prostanoid EP3 receptor antagonists synthesized at Bayer

IBD Therapeutics discloses TRPM8 and TrpV1 antagonists/opioid receptor agonists

Mouse model reveals role of Rap1A in heart function

Developmental origins of pediatric brain tumors

Study links long non-coding RNAs to pulmonary hypertension

Vi-DT typhoid conjugate vaccine begins phase III study in Nepal

Pharmacodynamic responses seen with RNA interference therapy ARO-ANG3 in healthy volunteers

Aslan reports preliminary proof-of-concept data on ASLAN-004 in atopic dermatitis

Proof-of-concept study of SENS-111 in acute unilateral vestibulopathy misses primary endpoint

Concert initiates phase II study of CTP-692 as adjunctive treatment in schizophrenia

Phase IIb trial of Amphora for prevention of chlamydia and gonorrhea meets primary endpoint

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