BioWorld Science

Jan. 10, 2020

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Gracell begins study of GC-027 for relapsed or refractory T-cell malignancies

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PERKing up astrocytes fights prion neurodegeneration

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First-in-human data presented for BCMA-CD19 cCAR T-cells

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Human CD83 CAR T cells for the prevention of GvHD and treatment of AML

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Positive 6-month data from ongoing phase I/II study in X-linked retinitis pigmentosa

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Regeneron announces phase II data for garetosmab in fibrodysplasia ossificans progressiva

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Phase III CONSTANT trial of Sci-B-Vac meets primary and secondary endpoints

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Locus begins phase Ib trial of CRISPR Cas3-enhanced bacteriophage product LBP-EC01

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Novartis patents new compounds for leishmaniasis and trypanosomiasis

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Dana-Farber Cancer Institute discloses new EGFR inhibitors

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Aduro BioTech identifies cGAS inhibitors

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Drexel University synthesizes new HIV capsid assembly inhibitors

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Heptares Therapeutics discovers muscarinic M1 and/or M4 receptor agonists

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Inhibrx initiates phase I study of hexavalent OX40 agonist INBRX-106 for solid tumors

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Redx Pharma nominates ROCK2 inhibitor RXC-007 as drug development candidate in fibrosis

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Biallelic loss-of-function variants in NADSYN1 cause congenital NAD deficiency and malformations

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CBX-12 announced as Cybrexa Therapeutics' lead development program

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Entrada announces development of ENTR-501 for mitochondrial neurogastrointestinal encephalomyopathy

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Transgenic CD2-Lmo2/Ldb1 knockout mouse model of T-ALL

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ELP5 found to be involved in gemcitabine sensitivity in gallbladder cancer

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Sellas opens enrollment in phase III trial of galinpepimut-S for AML

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Aclaris reports phase I data on oral MK2 inhibitor ATI-450

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FDA approves Ayvakit for unresectable or metastatic PDGFRA exon 18 mutant GIST

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