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BioWorld Science

Jan. 10, 2020

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Gracell begins study of GC-027 for relapsed or refractory T-cell malignancies

PERKing up astrocytes fights prion neurodegeneration

First-in-human data presented for BCMA-CD19 cCAR T-cells

Human CD83 CAR T cells for the prevention of GvHD and treatment of AML

Positive 6-month data from ongoing phase I/II study in X-linked retinitis pigmentosa

Regeneron announces phase II data for garetosmab in fibrodysplasia ossificans progressiva

Phase III CONSTANT trial of Sci-B-Vac meets primary and secondary endpoints

Locus begins phase Ib trial of CRISPR Cas3-enhanced bacteriophage product LBP-EC01

Novartis patents new compounds for leishmaniasis and trypanosomiasis

Dana-Farber Cancer Institute discloses new EGFR inhibitors

Aduro BioTech identifies cGAS inhibitors

Drexel University synthesizes new HIV capsid assembly inhibitors

Heptares Therapeutics discovers muscarinic M1 and/or M4 receptor agonists

Inhibrx initiates phase I study of hexavalent OX40 agonist INBRX-106 for solid tumors

Redx Pharma nominates ROCK2 inhibitor RXC-007 as drug development candidate in fibrosis

Biallelic loss-of-function variants in NADSYN1 cause congenital NAD deficiency and malformations

CBX-12 announced as Cybrexa Therapeutics' lead development program

Entrada announces development of ENTR-501 for mitochondrial neurogastrointestinal encephalomyopathy

Transgenic CD2-Lmo2/Ldb1 knockout mouse model of T-ALL

ELP5 found to be involved in gemcitabine sensitivity in gallbladder cancer

Sellas opens enrollment in phase III trial of galinpepimut-S for AML

Aclaris reports phase I data on oral MK2 inhibitor ATI-450

FDA approves Ayvakit for unresectable or metastatic PDGFRA exon 18 mutant GIST

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