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BioWorld Science

Feb. 12, 2020

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Plexin D1 is receptor and mechanosensor in 1

Multiple edits make for durable T cells

The genetic architecture of tumors induced by high and low energy radiation in Trp53 deficient mice

Novartis studies BLZ-945 in phase II trial for ALS

TaiMed studies TMB-365 in first-in-human trial for HIV-1

FDA places clinical hold on the IND submission for LB-001

Positive top-line data from a phase II study of DAV-132

Plinabulin is a potent stimulator of the adaptive and innate immune system

TBX21 as a new genetic target in colorectal cancer

Prolactin could explain sex differences in pain syndromes

Roche patents new TLR antagonists

Cadila Healthcare discloses new compounds for tuberculosis

CVie Therapeutics and UNIMIB divulge compounds for heart failure

Faes Farma identifies new histamine H4 receptor antagonists

Esteve Pharmaceuticals discloses new analgesics

Phase IIb results presented for dalcinonacog alfa in hemophilia B patients

Xtandi significantly improves OS in PROSPER trial in non-metastatic CRPC

Aptorum reports data from IND-enabling studies of ALS-4 to treat S. aureus infections

Antios initiates first-in-human study of ATI-2173 for hepatitis B

Allena plans protocol amendment for second pivotal trial of reloxaliase for enteric hyperoxaluria

VistaGen reports preclinical data on AV-101 transport with adjunctive probenecid