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BioWorld Science

Feb. 21, 2020

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New search method, new antibiotic MOA

JAK inhibitors build bone, no inflammation necessary

FDA approves IND application for phase IIb study of CMN-001 in advanced RCC

Passengers, noncoding genome affect how cancers play out

Mesoblast reports clinically meaningful outcomes for remestemcel-L in chronic GVHD

Enrollment ongoing in phase I/II study of MB-102

Novartis initiates first-in-human trial of WVT-078 in multiple myeloma

VBL initiates phase II study of VB-111 and nivolumab in metastatic colorectal cancer

Results from ongoing phase I study of ciforadenant with or without atezolizumab in mCRPC

BT-200 blocks VWF and platelet function in whole blood of patients with acute stroke

AT-845 shows safety and robust efficacy in preclinical models

New CDK8/19 inhibitors described by Biocad CJSC

Bristol-Myers Squibb discovers toll-like receptor 7 agonists

Sumitomo Dainippon Pharma describes anticancer chromen derivatives

Artios Pharma patents DNA polymerase eta inhibitors

Antabio SAS discovers serine beta-lactamase inhibitors

Oncofid-P-b shows promise in bladder cancer patients unresponsive to BCG

Chloroquine phosphate improves COVID-19-associated pneumonia in patients

EncuraGen presents new ADIPOR1 agonist BHD-1028 for type 2 diabetes, obesity and NASH

Phase IIb/III study of oral masitinib in PPMS and nSPMS meets primary endpoint

FDA approves Anjeso for moderate to severe pain

New phase I/IIa trial studies IHA infusion of TG-6002 for liver metastases from colorectal cancer

Agenus reports new data from cancer immunotherapy programs

Opdivo approved in Japan for advanced esophageal cancer

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