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BioWorld Science

Feb. 26, 2020

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Oligodendrocyte-neural connections not just about myelin

Sharper look yields new potential kinase target in ovarian cancer

DOTATATE uptake is higher in mCRPC patients with neuroendocrine transformation

Circulating ANGPTL8 as a marker of metabolic disorders in PCOS

Results from phase Ib portion of the CARTITUDE-1 study

Pandion begins first-in-human trial of PT-101 for autoimmune disease

Preclinical data presented for scAAV9/CLN7 gene replacement therapy

Trinucleotide expansions are too much of a good thing

Optimization and in vivo testing of bumetanide derivatives for temporal lobe epilepsy

Aclaris Therapeutics patents ITK and JAK3 inhibitors

Study of CoV-OC43 dissemination in mouse CNS and drug testing using non-invasive bioluminiscence

Structure-based screening unveils new melatonin receptor ligands that modulate circadian rhythms

Sitari Pharma divulges TGM2 inhibitors

Defibrotide safe in young patients with sickle cell disease undergoing stem cell transplantation

Inorbit Therapeutics AB synthesizes new NR1H4 agonists

University of Texas System identifies new PTPN11 inhibitors

Incyte patents MAP4K1 inhibitors

Tradipitant demonstrates antipruritic effect in mild atopic dermatitis in phase III EPIONE study

ProMIS announces pilot longitudinal study to assess blood-based biomarkers for Alzheimer's