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BioWorld Science

April 2, 2020

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Ditching PAMs expands CRISPR

In blood stem cells, selection drives driver mutations early on

FDA accepts IND application for OTQ-923

Johnson & Johnson announces new lead COVID-19 vaccine candidate

Positive phase II data for THN-102 in patients with Parkinson's disease and EDS

DSR-141562 shows promise in preclinical schizophrenia-related behavioral assays

DIF-1 shows antimetastatic effects in malignant melanoma cells

CRMP2 as a novel biomarker for schizophrenia

Researchers mimic interstitial cystitis in rat model

Biochemical Agent describes IGF-1 long chimeric proteins

New potent and selective ATP-competitive mTOR inhibitor with brain penetrance for CNS disorders

Ohio State University patents lipid nanoparticles modulating Bcl-2, Akt-1

Novel series of sulfamoylbenzamides modulating capsid assembly to target hepatitis B virus infection

Yale University, Arvinas Operations disclose new PROTAC compounds

Primmune selects PRTX-007 for development for SARS-CoV-2 prophylaxis

New RIP-1 inhibitors identified at Bristol-Myers Squibb

FORMA Therapeutics identifies new pyruvate kinase PKLR activators

Accelerated by COVID-19, science changes will outlast pandemic

Step-1 primary endpoint met in phase III Atalante 1 trial of Tedopi in NSCLC

FDA approves Sevenfact for hemophilia A and B

Nicotinic acetylcholine receptors as potential target for treating synucleinopathies

Interim analysis from study of siltuximab in patients with COVID-19 and respiratory complications

Arena reports topline phase I data on controlled-release etrasimod

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