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BioWorld - Monday, March 16, 2026
Home » Newsletters » BioWorld Science

BioWorld Science

April 14, 2020

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Dual mu-opioid/nociceptin receptor agonist BPR-1M97 shows advantages over morphine

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Death, taxes and zoonotic spillover

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Phase I trial of INO-5150 immunotherapy against PSA/PSMA in biochemically relapsed prostate cancer

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An innovative 3D fiber-reinforced hydrogel for the regeneration of corneal stroma

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Exosomes deliver sepsis treatment

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Dopamine has epigenetic role in addiction

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Koselugo receives FDA approval for pediatric patients with NF1-related plexiform neurofibromas

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Metacrine patents farnesoid X receptor agonists

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SOX4-dependent regulation of a subset of tRNA genes controls human glioblastoma cell proliferation

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New melanocortin MC4 receptor agonists identified at Palatin Technologies

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Bristol-Myers Squibb discovers lysophosphatidic acid receptor 1 antagonists

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Loss-of-function mutation in BK channel reduces mitochondrial viability, causing progressive ataxia

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Phase III study of tislelizumab plus chemotherapy in NSCLC meets primary endpoint

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Roche, Genentech describe new MAP4K1 inhibitors

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FDA lifts clinical hold on phase III study of TG-C

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New small-molecule inhibitor of enterovirus 71 for the treatment of hand, foot and mouth disease

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Goldfinch Biopharma presents new TRPC5/TRPC4 antagonists

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Potent and selective sphingosine kinase 2 inhibitor targeting a small side cavity

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Ridgeback Biotherapeutics initiates phase I study of EIDD-2801 for COVID-19

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PLOD1 mutation tied to smooth muscle cell dysfunction and aortopathy

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Bausch Health initiates clinical trial of Virazole in patients with COVID-19

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BioInvent reports early responses in phase I/IIa study of BI-1206 for NHL

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AstraZeneca to unblind phase III ADAURA trial of Tagrisso early based on efficacy

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Lilly advances plans to evaluate baricitinib and LY-3127804 for COVID-19

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