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BioWorld Science

April 20, 2020

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Engineering better bacterial backstabbers

Targeting bystander protein improves sepsis outcome

Phase II study of Ad5-nCoV vaccine in healthy adults

Revive partners with Complete Phytochemical Solutions to develop psilocybin-based products

New spiroindoline derivatives show potential as remyelinating agents

PS-PLA1 as new therapeutic target in hyperthyroidism disorders

Chinese researchers patent RET inhibitors

Medshine Discovery presents new TRK inhibitors

Beijing Heli Consulting identifies polypeptide conjugates of odanacatib

Nanjing Gentai Pharmaceutical Technology identifies BTK inhibitors

Cancer drug delivery system targets tumor extracellular matrix, avoids healthy tissue

Roche describes new TLR antagonists

Ribonucleoside analogue EIDD-1931 is potently active against coronaviruses

New genetic variants in SLC34A2 gene tied to lung microlithiasis

Pemazyre approved in U.S. for advanced cholangiocarcinoma with FGFR2 fusions or rearrangements

FDA clears anti-Claudin 18.2 antibody TST-001 to enter clinical trials for metastatic solid tumors

FDA approves Tukysa for advanced, unresectable or metastatic HER2-positive breast cancer

Initiation of phase III RUXCOVID trial of ruxolitinib for COVID-19-associated cytokine storm

Novartis plans phase III study of hydroxychloroquine in hospitalized patients with COVID-19 disease

Idorsia reports first pivotal results with daridorexant in insomnia

U.K. MHRA clears 4D Pharma to begin phase II study of MRx-4DP0004 in COVID-19

Ascendis reports fixed-dose TransCon PTH data from phase II PaTH Forward trial in hypoparathyroidism

Kazia updates findings from phase I study of Cantrixil in ovarian cancer

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