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BioWorld Science

April 28, 2020

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Heart failure hormone has role in sepsis

NRF2 wakes sleeping tumor cells

FDA grants IND approval for phase III study of GV-971 in Alzheimer's disease

Pivotal ADVANCE-1 study of AXS-05 meets primary endpoint

FDA approves Ongentys as add-on treatment for patients with Parkinson's disease

Preclinical data support development of FX-301 for post-operative pain

Pilot study data for ZX-008 as adjunctive therapy in sunflower syndrome

Adavosertib shows clinical activity in uterine serous carcinoma

Pliant Therapeutics discovers integrin alphavbeta1 and/or alphavbeta6 antagonists

New ROMK blockers identified at Bristol-Myers Squibb

NantBioScience patents dual Wnt/beta-catenin and hedgehog signaling inhibitors

New TLR7 agonist prodrugs disclosed by Jiangsu Hengrui Medicine, Shanghai Hengrui Pharmaceutical

Boehringer Ingelheim identifies new plasma kallikrein inhibitors

[11C]MK-6884 useful for muscarinic receptor imaging in AD

AACR 2020: Phosphatases are yin to kinases' yang

ENTR-501 corrects metabolic abnormalities in mouse model of MNGIE

European Commission approves Fetcroja for infections due to aerobic Gram-negative bacteria

Genuv studies trametinib in phase I/IIa trial in Korea for ALS

Enrollment open in phase I/IIa study of PBCAR-269A in relapsed/refractory multiple myeloma

First-in-human data for the ChAdOx1 MERS vaccine candidate

BXCL-701 advances into phase II portion of phase Ib/II trial with pembrolizumab for tNEPC

Roche reports new 6-year data on Ocrevus in MS

FIREFISH part 2 study of risdiplam in infants with type 1 SMA meets primary endpoint

Sovateltide demonstrates improvement on mRS in acute ischemic stroke trials