BioWorld Science

May 7, 2020

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Polymerase kappa and drug resistance

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Sphingolipids accumulate in neurodegeneration

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Carbohydrate metabolism implicated in neuropathy

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Merck & Co. presents data from RESTORE-IMI 2 phase III study of Recarbrio

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TGen and HonorHealth initiate study of atovaquone plus azithromycin in COVID-19

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Topline data shows multifactorial activity of AXA-1125 and AXA-1957 in NAFLD

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Nimbus Lakshmi patents TYK2 inhibitors

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First-in-human data presented for KA-2507

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NiKang Therapeutics synthesizes new HIF-2alpha inhibitors

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Merck & Co. identifies IDO1 inhibitors

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Suven Life Sciences describes new muscarinic M1 receptor PAMs

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New SERPINA1 modulators presented by Vertex Pharmaceuticals

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EOS-100850 shows excellent tolerance and clinical benefit in refractory solid tumors

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New mouse model of mild spinal muscular atrophy

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Amgen reports topline data from phase III study of Otezla for mild to moderate plaque psoriasis

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New phase III study evaluates lenzilumab in hospitalized patients with COVID-19

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DongWha Pharm plans phase II evaluation of DW-2008 for COVID-19

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HIF-1alpha stabilizer GB-004 well tolerated in multiple-dose phase I study

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Lineage Cell Therapeutics updates phase I/IIa results with OpRegen for dry AMD

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FDA approves Elyxyb for acute treatment of migraine with or without aura

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Enanta reports topline phase II data on EDP-305 in primary biliary cholangitis

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FDA approves Tabrecta for metastatic NSCLC with METex14

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FDA clears new phase I study of NBTXR-3 activated by radiation therapy for pancreatic cancer

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