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BioWorld Science

May 12, 2020

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Prying mantis identifies disease genes

T-cell mutations contribute to GvHD

TLR5 is a therapeutic target for treating chronic colonic hypersensibility

NIH initiates ACTT 2 study of remdesivir plus baricitinib in patients with COVID-19

Novel peptide-targeted approach improves potency of anticancer drugs

PK and PD data presented for OPL-002 in healthy volunteers

CPU-025 demonstrates promising efficacy in mouse model of diabetes

Array BioPharma discloses new PTPN11 inhibitors

Dana-Farber Cancer Institute, Voronoi patent wild-type and mutant LRRK2 inhibitors

New histone-lysine N-methyltransferase SMYD3 inhibitors identified at Epizyme

Wild-type and mutant RET inhibitors identified at Medshine Discovery

Dual adenosine A2A/A2B receptor antagonists described by Merck KGaA

Via gene therapy, follistatin fights fat's fallout

New POLG genetic variant found in SANDO syndrome

ONSET-2 trial of OC-01 in dry eye disease meets primary endpoint

Phase III study of mavacamten in obstructive hypertrophic cardiomyopathy meets endpoints

Kiniksa reports data on mavrilimumab for COVID-19 and vixarelimab for pruritus

Boehringer Ingelheim studies BI-456906 for type 2 diabetes in new phase II trial

Canakinumab studied in phase III for CRS in patients with COVID-19-induced pneumonia

Enrollment underway for first-in-human study of BRAF inhibitor ABM-1310 in advanced solid tumors

Ustekinumab efficacy demonstrated in pediatric Crohn's disease patients

Phase I study of BRD4 inhibitor SYHA-1801 begins for advanced solid tumors

FDA clears IND for phase Ib/IIa study of HST-001 for androgenic alopecia

Phase III study of Sarclisa in relapsed multiple myeloma meets primary endpoint

Genfit reports phase III interim data on elafibranor in NASH

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