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BioWorld Science

June 3, 2020

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Novel NLRP3 inflammasome inhibitors as potential treatments of chronic inflammatory diseases

First-in-human data reported for Ad5 vectored COVID-19 vaccine

General method for taking out specific Gram-negatives

Kinase helps prepare pre-metastatic niche

Proteostasis Therapeutics reports in vitro data on UPR modulator PTI-129 for COVID-19

Lilly initiates phase I study of LY-CoV555 for COVID-19

Sarclisa approved in Europe for adults with relapsed and refractory multiple myeloma

Danish Medical Agency approves CTA application for AP-1189 in nephrotic syndrome

Trevena and Imperial College London collaborate to evaluate TRV-027 in patients with COVID-19

Maximum tolerated dose identified with positive safety profile for CC-92480 in multiple myeloma

Nimbus Artemis describes new ATP-citrate synthase inhibitors

FDA clears IND application for SNK-01 in combination with trastuzumab or cetuximab

MAP3K5 inhibitors discovered at Enanta Pharmaceuticals

Preliminary safety data reported from ILLUMINATE-206 study

Bayer patents cytostatic conjugates with integrin alphavbeta3 ligands

Topline data from pivotal phase III True North trial of Zeposia in ulcerative colitis

New PI3K-gamma inhibitors disclosed by Incyte

Beijing Reciproca Pharmaceuticals identifies new Bruton tyrosine kinase inhibitors

Description of a potential COVID-19 mouse model presenting human ACE2 and TMPRSS2 genes

Efficacy and safety reported for alflutinib in NSCLC patients with EGFR T790M mutation

Tenax Therapeutics reports positive phase II results for levosimendan in PH-HFpEF

Topline data announced from phase IIb study of gusacitinib in chronic hand eczema

FDA gives clearance to phase I study of CK-0802 in COVID-19-associated ARDS

Favorable results seen with immunotherapy OH-2 in patients with advanced solid tumors

Enrollment starts in phase I study of WP-1066

First-in-human data presented for of SRF-231

FDA clears IND for phase I/II study of Altimmune's T-COVID

Intravacc and EpiVax collaborate to advance novel COVID-19 vaccine

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