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BioWorld - Friday, April 17, 2026
Home » Newsletters » BioWorld Science

BioWorld Science

June 19, 2020

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Discovering pharmacological enzyme activators

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ShanghaiTech University presents new estrogen receptor protein regulators

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Clinical activity seen with bomedemstat in phase II study in advanced myelofibrosis

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Positive topline phase II data for XP-3924 in type 1 diabetes mellitus

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SETD2 as biomarker of overall survival in systemic mastocytosis

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Novel humanized immunocompetent mouse model to study DCP-001 vaccine

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Mutations in GBF1 associated with hereditary motor neuropathy

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Merck & Co. discovers adenosine receptor A2A and/or A2B antagonists

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Nimbus Lakshmi identifies new TYK2 inhibitors

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Bristol-Myers Squibb patents FPR1/FPR2 agonists

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New androgen and/or glucocorticoid receptor antagonists synthesized at Nuvation Bio

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Phase I data presented for PF-06882961 in patients with type 2 diabetes

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New peripheral 5-HT2A antagonists for NAFLD treatment by structural modification of pimavanserin

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Neutralizing MAb from a convalescent patient inhibits SARS-CoV-2 infection in preclinical models

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ZSCAN12 gene linked to congenital lower urinary tract obstruction

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Innovent begins phase Ib/II trial of IBI-362 in overweight or obese subjects in China

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Reistone begins dosing in phase II study of SHR-0302 for alopecia areata

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Parkinson's findings have implications for models, targets, publications

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FDA approves Crysvita for tumor-induced osteomalacia

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Durvalumab/tremelimumab immunotherapy effective with chemotherapy in biliary tract cancer

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FDA grants accelerated approval to Tazverik for relapsed/refractory follicular lymphoma

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Loss-of-function mutation in CCDC134 gene tied to severe osteogenesis imperfecta

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Amgen begins phase III trial with AMG-510 for NSCLC with KRAS p. G12c mutation

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FXR agonist TERN-101 enters phase IIa study for NASH

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Clover's COVID-19 vaccine candidate enters first-in-human study

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First-in-human study evaluates GT-103 in refractory advanced NSCLC

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