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BioWorld Science

June 25, 2020

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The bow ties that bind

FOXO1 regulates HIV latency

Novel candidate genes identified for Hirschsprung's disease

Positive data presented from SPIRIT 1 study of relugolix combination therapy in endometriosis

The role of c-Rel in the generation of suppressive myeloid cells that promote cancer

GOLT1A-KISS1 gene fusion has a metastatic role in adenoid cystic carcinoma and other cancer types

BTK inhibitors may decrease the pathological inflammatory response in severe COVID-19 patients

Seelos presents final phase I safety data for SLS-002 and additional clinical development plans

Enrollment of first patient in phase II study of pamrevlumab in acute COVID-19

Palatin to develop PL-8177 for the treatment of COVID-19 and associated lung complications

Amgen supports further development of AMG-634

SIK3 inhibitor OMX-0370 shows promising antitumor activity

Rohto Pharmaceutical to evaluate ADR-001 in patients with COVID-19 severe pneumonia

USP53 identified as a causal gene for intrahepatic cholestasis

Loss-of-function variants in TBC1D2B linked to neurodevelopmental disorder with seizures

AGILeBiotics patents new antibacterials

Merck KGaA divulges new tankyrase inhibitors

Hangzhou Innogate Pharma presents new CDK and HDAC dual inhibitors

Esteve Pharmaceuticals discloses new analgesics

Chinese researchers divulge S1P receptor 1 agonists

European phase III study of MOB-015 for onychomycosis meets primary endpoint

Poxel reports PK/PD study data on PXL-770 in likely NASH patients with insulin resistance

Berlin Cures plans to evaluate BC-007 for COVID-19

Phase II data support progression of arimoclomol into pivotal-stage development in Gaucher disease

AACR Virtual Meeting II: Combination therapies: Searching for synergy

Phase III study of Ultomiris SC in PNH meets primary endpoint

MediGene receives Dutch clearance to begin phase I trial of MDG-1021 in hematological cancers

FDA approves Keytruda for recurrent or metastatic cutaneous squamous cell carcinoma

FDA clears IND for phase II study of NRD135S-E1 in painful diabetic peripheral neuropathy

Biohaven to advance troriluzole for OCD based on phase II/III proof-of-concept results

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