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BioWorld Science

July 14, 2020

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Base editor targets mitochondrial DNA

KPG-121, a cereblon modulator, shows promising antitumor activity in vitro and in vivo

Recombinant Bifidobacterium longum APS-002 secretes T-cell-redirecting diabody DBERB1

Metagenomic data aid phage therapy development

Discovery of KB-00130742 as orally bioavailable and ultra-selective inhibitor of CDK9

CCX-6569 shows promising antitumor activity in model of colon adenocarcinoma

Huihan Medical Technologies discloses new Wnt signaling inhibitors

Merck & Co. describes new anti-HIV compounds

New bacterial DNA gyrase/DNA topoisomerase IV inhibitors discovered at Roche

PharmaBlock Sciences identifies influenza virus replication inhibitors

Novel SSTR antagonist [177Lu]DOTA-LM3 shows promising results in patients with NENs

Novartis patents mutant CFTR correctors

Positive preclinical data for AdCOVID intranasal COVID-19 vaccine candidate

New sulfonamide derivatives as potent, selective and state-dependent Nav1.7 inhibitors for pain

BAN-2401 to be evaluated in new phase III AHEAD 3-45 program

Shanghai Junshi and Revitope enter into research collaboration and license agreement

Results of a phase III trial of reltecimod in severe necrotizing soft tissue infections

Dewpoint and Merck & Co. collaborate to develop condensate-based drug candidates against HIV

Interim phase I data presented for CTT-1403 in mCRPC

MHRA grants early access to lumasiran in the U.K.

INmune Bio reports interim phase Ib data on XPro-1595 in Alzheimer's disease

First patient dosed in OLE/switch study of FT-218 in narcolepsy

Immunomedics and Roche expand collaboration to study Trodelvy with Tecentriq

Innovation Pharmaceuticals provides updates regarding clinical testing of brilacidin in COVID-19

Arcutis begins phase IIb portion of phase I/IIb study of ARQ-252 for chronic hand eczema

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