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BioWorld Science

Aug. 7, 2020

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TXNIP inhibition nixes T2D

Supportive preclinical reported for PTX-COVID19-B vaccine candidate

First-in-human data presented for NTRX-07

Daiichi Sankyo patents new SIRT6 activators

Merck & Co. synthesizes HDAC inhibitors

Chinese researchers identify LPAR1 antagonists

Innate Tumor Immunity discloses NLRP3 agonists

New adenosine A2A receptor antagonists discovered by Nuvation Bio

Boehringer Ingelheim initiates first-in-human study of BI-764532

Structure-guided analysis unveils the mechanism of action of a dengue virus 2-specific inhibitor

SASS6 is involved in the proliferation of esophageal cancer and may be a novel therapeutic target

AstraZeneca is enrolling participants in phase I study of MEDI-8367

First patient enrolled in phase IIb/III study of ifenprodil for treatment of COVID-19

Six-month follow-up data announced from phase I study of INXN-4001

Anti-podocalyxin [225Ac]PODO-447 shows promise as immunotherapeutic for treating solid tumors

Dicerna provides data updates from clinical and preclinical developments

Topline data presented from phase III CARE-PWS study of LV-101

Phase II/III study of opaganib in patients with COVID-19 receives approval in Mexico

FDA clears IND for phase II study of TNX-102 SL

First patient dosed in a phase Ib/II study FGF-401 plus pembrolizumab

Study links mitochondrial DNA to abscopal response

Roche gives update on phase III IMpassion131 study of Tecentriq

GlycoNex initiates phase I study of GNX-102

First-in-human study of DC immunotherapy in patients with pancreatic adenocarcinoma

EC approves Xolair as treatment of severe chronic rhinosinusitis with nasal polyps

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