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BioWorld - Saturday, December 6, 2025
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BioWorld Science
Sep. 14, 2020
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Faulty exon splicing is cause of rare subtype of Parkinson's disease, pointing to new drug targets
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Positive preclinical data for novel COVID-19 vaccine, ACvac1
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Key initial results reported from phase I study of CPI-006 for patients with COVID-19
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FDA clears IND for phase I study of APR-003
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Room for improvement in T-cell repertoire profiling
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Results from phase II CENTAUR study of sodium phenylbutyrate/taurursodiol in ALS
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Voronoi patents new RET inhibitors
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Galapagos discloses PASK inhibitors
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Aerie Pharmaceuticals presents new Rho and JAK inhibitors
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Discovery of novel orally active and selective PI3Kalpha inhibitor
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Constellation Pharmaceuticals discovers new CBP and KAT3B inhibitors
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New phase II trial examines suprachoroidal administration of AU-011 in primary choroidal melanoma
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Proof-of-concept study of ziritaxestat in diffuse cutaneous systemic sclerosis meets endpoint
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New antibacterials presented by Viridias
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Topadur begins phase I study of TOP-N53 for wound healing
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QBW-251: a CFTR potentiator in phase II for the treatment of COPD
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Phase III trial of Fasenra in nasal polyposis meets coprimary endpoints
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Bicycle opens phase I/II study of BT-8009 in advanced solid tumors
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FCN-437c enters phase II trial in China for advanced breast cancer
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Pentamidine targets S100B to improve experimental multiple sclerosis
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SanBio reports new phase IIb analyses for SB-623 in chronic motor deficit from ischemic stroke
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Gemini begins phase IIa study of GEM-103 for dry AMD
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Novartis describes discovery and clinical results with ERK1/2 inhibitor LTT-462
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Sutro reports updated phase I data on STRO-002 in advanced ovarian cancer
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KITE study of Beovu in DME meets primary and key secondary endpoints
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Dimerix reports phase II data on DMX-200 in diabetic kidney disease
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Enanta begins phase I study of EDP-297 for NASH
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FDA approves Trelegy Ellipta for asthma
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