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BioWorld Science

Sep. 23, 2020

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Glial metabolism affects neural recovery

Kemp Proteins to provide assay development for first-in-class chronic SCI therapy, AXER-204

Genentech and Roche divulge new antibacterials

Gilead Sciences presents new PKC agonists

First-in-human study of IGM-8444 begins in patients with solid tumors

AbbVie and Galapagos identify CFTR mutant correctors

New potential broad-spectrum fungicides discovered

Phase I data for sotorasib in advanced solid tumors harboring the KRAS p.G12C mutation

Researchers develop mouse-adapted SARS-CoV-2 model causing age-related disease pathogenesis

Cyteir Therapeutics describes RAD51A inhibitors

REVOLUTION Medicines patents SOS1 inhibitors

P2X4R inhibition reduces proinflammatory myeloid cells, offering neuroprotection after stroke

First clinical data presented for first-in-class NOTCH inhibitor CB-103

Henlius reports phase III data on bevacizumab biosimilar HLX-04

First-in-human study evaluates AZD-8701 alone and with durvalumab in advanced solid tumors

Debio-1143 studied in phase III with chemoradiotherapy for locally advanced SCCHN

M-8891 has manageable safety profile and favorable PK in first-in-human study

ILT4 antibody MK-4830 well tolerated, shows encouraging responses in phase I study

First-in-human data presented for TLD-1

Micreos begins phase I/IIa study of endolysin XZ.700 in atopic dermatitis

Durect eyes initiation of phase IIb trial of DUR-928 in alcoholic hepatitis

Vaccinex reports topline phase II data on pepinemab in Huntington's disease

FDA accepts IND for adoptive T-cell therapy GEN-011

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