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BioWorld Science

Sep. 30, 2020

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Buyer beware for SARS-CoV-2 antibody detection

Breathing new life into obsolete antibiotics

Sorrento reports preclinical data on COVI-GUARD and COVI-AMG for COVID-19

Heparan sulfate acts as a coreceptor of SARS-CoV-2, priming the spike protein for ACE2 interaction

Bifunctional hybrid nanoscaffold for SCI: anti-inflammation and biomimetic neural matrix formation

Interim data from phase I/IIa study of Janssen's COVID-19 vaccine candidate

Moleculin discovers new antimetabolites with significant in vitro activity against COVID-19

FDA accepts IND application for lucinactant in COVID-19-associated acute lung injury

Positive topline phase I data for ROSgard in patients with renal impairment

Lipid metabolism controls lung cancer metastasis, not just diseases like atherosclerosis

Biogen identifies new N-acetyl-beta-D-glucosaminidase inhibitors

Janssen presents anti-hepatitis B virus compounds

ER Stress Research Institute patents eIF-2-alpha inhibitors

Universidade Nova de Lisboa and collaborators describe new free radical scavengers/antioxidants

Pembrolizumab in first-line esophageal cancer: first data from KEYNOTE-590

New IL-7 modulators discovered at Leo Pharma

AK-104 demonstrates safety and antitumor activity in patients with mesothelioma

Sarepta reports data from ongoing first-in-human study of SRP-9003 for LGMD2E

Oncternal Therapeutics presents phase I data for TK-216

REG-1-alpha identified as a marker of gestational diabetes

FDA approves Xeljanz for active polyarticular course juvenile idiopathic arthritis

Ironwood to discontinue IW-3718 for GERD

Zucara initiates phase I study of ZT-01 to prevent insulin-induced hypoglycemia in type 1 diabetes

FDA accepts IND for phase IIb study of AR-15512 in dry eye disease

New phase III trial to evaluate bucillamine in COVID-19

Arcutis reports topline phase II data on roflumilast topical foam for seborrheic dermatitis

Regeneron reports data on REGN-COV2 in nonhospitalized patients with COVID-19

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