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BioWorld Science

Nov. 4, 2020

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Cutting off AML's metabolic escape route

Challenges for mutation correction in human embryos

FDA approves Bronchitol inhalation powder for patients with cystic fibrosis

Innovation Pharmaceuticals receives pre-IND response for brilacidin trial in COVID-19

FDA clears IND application for phase I/II study of EG-70 in NMIBC

Adakveo approved in Europe to prevent VOCs in patients with sickle cell disease

Concert initiates phase III THRIVE-AA1 study of CTP-543 for alopecia areata

AT-752 improves survival in mouse model of dengue infection

Nurix Therapeutics patents CBLB inhibitors

Plexxikon discloses KAT3B and CREBBP inhibitors

Bristol Myers Squibb identifies new Gal-3 inhibitors

Nuvation Bio describes new Wee1 inhibitors

Tenaya Therapeutics presents AAV5 compositions

Serine deprivation spurs selective translation in pancreatic cancer

JCR begins global phase I/II trial of JR-171 for MPS I

Combination of donepezil and quetiapine or PDE10A inhibitors provides synergic anti-BuChE activity

Phase III results for molidustat in patients with renal anemia undergoing dialysis

LV20.19, a bispecific CAR T-cell therapy for RR B-cell malignancies: results from phase I trial

Biodistribution, dosimetry and preclinical efficacy data presented for [177Lu]rhPSMA-7.3

New PROTACs synthesized by C4 Therapeutics

BiomX begins first-in-human study of BX-002 phage therapy for IBD

Phase II/III study of voclosporin ophthalmic solution in dry eye does not meet primary endpoint

IO Biotech announces new phase II trial of cancer immunotherapies in head & neck cancer

Aligos begins first-in-human trial of ALG-000184 for chronic hepatitis B

HT-005 reduces skin plaque severity in cutaneous lupus erythematosus mouse model