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BioWorld Science

Dec. 2, 2020

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Junshi Biosciences provides updates on JS-108 and JS-006 studies

FDA accepts IND for CERC-803 to treat leukocyte adhesion deficiency type II

Phase III ACTIVATE trial of mitapivat in PK deficiency meets primary endpoint

RS-5614 studied in investigator-initiated trial for severe COVID-19

Combination enhances solid tumor immunotherapy

Edesa initiates phase II/III study of EB-05 for hospitalized patients with COVID-19

Investigator-initiated trial to study Carragelose nasal spray for COVID-19 prophylaxis

Preliminary week 18 phase Ib/IIa data reported for HST-001 in androgenic alopecia

Rafael Pharmaceuticals to launch phase II study of CPI-613 in clear cell sarcoma of soft tissue

Agenus initiates phase II expansion of AGEN-1181 plus balstilimab in colon cancer

DMC completes positive safety review of CYNKCOVID study

Korea Research Institute of Bioscience and Biotechnology patents peptides for IBD

New USP19 inhibitors described by Integral Health Holdings, Valo Early Discovery

Aligos Therapeutics discovers STING agonists

FDA grants accelerated approval to Gavreto for advanced or metastatic RET-altered thyroid cancers

Prodrugs of TLR7 and TLR8 antagonists identified at Bristol Myers Squibb

New JAK inhibitors patented by Vimalan Biosciences

FDA approves Xolair to treat nasal polyps

Hetlioz approved in U.S. for nighttime sleep disturbances in Smith-Magenis syndrome

Investigators develop a swine model of abdominal aortic aneurysm

Targovax reports phase I data on ONCOS-102 with pembrolizumab in advanced melanoma

Novel rat models of doxorubicin-induced left ventricular dysfunction

A-3907 targets bile acid transport in the intestine and kidney for treating NASH, fibrosis

Ashvattha Therapeutics presents htHD-FXRa for treating hepatic and biliary disorders

Akeso reports preliminary data on cadonilimab for MSI-H advanced solid tumors

FDA clears IND for phase I study of DHOHD inhibitor RP-7214 for COVID-19

NEPTUNE study of OV-101 for Angelman syndrome misses primary endpoint

U.K. approval for Pfizer and BioNTech's COVID-19 mRNA vaccine BNT-162b2

IND for phase I study of SSAO/VAP-1 inhibitor TT-01025 cleared in U.S.

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