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BioWorld Science

Dec. 11, 2020

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How stress disrupts tumor cell sleep

Specific PARP1-PROTAC degrader shows anticancer activity in preclinical models

Formycon reports preclinical data on FYB-207 for COVID-19

Fluvoxamine may prevent clinical deterioration in mild symptomatic COVID-19 compared with placebo

NGM discloses novel antagonist antibody inhibiting LAIR1 for advanced solid tumors

Positive pivotal phase III data for Epolong in CKD

First patient dosed in pivotal ENVASARC study of envafolimab

Positive topline data presented from ULTIMATE I and II studies of ublituximab

PureTech initiates proof-of-concept study of LYT-100 in lymphedema

Pharvaris discovers B2 bradykinin receptor antagonists

New IDO-1 inhibitors presented by BeiGene

Shanghai Daoshang Biology Tech, Shanghai Medicilon patent MNK1 and MNK2 inhibitors

Mutant EGFR inhibitors presented by Jiangsu Hansoh Pharmaceutical Group, Shanghai Hansoh Biomedical

New SSAO inhibitors identified at Sunshine Lake Pharma

AbbVie reports phase IIIb head-to-head data on upadacitinib in atopic dermatitis

Hoth receives Australian clearance for phase Ib trial of BioLexa for atopic dermatitis

Variants in KCNH2 gene as predictive biomarkers of SUDEP risk

Bellicum initiates phase I/II trial of BPX-603 for HER2-positive tumors

Targeting filamin A reduces seizures in models of focal cortical malformations

TaiGen advances influenza antiviral TG-1000 into phase II study

WVE-004 developed as stereopure antisense oligonucleotide for C9orf72-associated ALS and FTD

Ascentage reports clinical data on APG-2575 in CLL

Fera to assess naproxcinod as adjuvant treatment for patients with COVID-19

Neoleukin submits IND application for NL-201 for relapsed or refractory solid tumors

Passage Bio receives first clearance for PBGM-01 clinical trial program for GM1 gangliosidosis

DNA nanostructure molecular gate allows protein-controlled transport of drugs

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