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BioWorld - Thursday, April 25, 2024
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BioWorld Science
Dec. 28, 2020
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Targeting GCGR signaling pathway counteracts PI3K inhibitor-induced hyperglycemia
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DISC-0974 decreases hepcidin and increases transferrin saturation in inflammation models
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First-in-human data presented for talquetamab in patients with RRMM
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Results of RCT evaluating nilotinib in patients with moderately advanced Parkinson's disease
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DISC-A demonstrates efficacy in low hepcidin rat model
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CTPS2 as novel prognostic biomarker in CLL
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FDA lifts clinical hold on ASPIRO study of AT-132
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Orelabrutinib approved in China for two cancer indications
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Shanghai Institute of Materia Medica, Fudan University patent PD-1/PD-L1 interaction inhibitors
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First subject dosed in phase I study of ASC-42
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National Institute of Pharmaceutical R&D describes M3 antagonists/beta2-adrenoceptor agonists
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New autotaxin inhibitors described by Jiangsu Hengrui Medicine, Shanghai Hengrui Pharmaceutical
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Medshine Discovery synthesizes new JAK1/JAK2 inhibitors
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New ERK inhibitors discovered at Hutchison MediPharma
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Byvasda approved in China the treatment of recurrent glioblastoma
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Arctic Vision obtains IND approval for ARVN-001 in China
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NX-2127 shows promising antitumor activity in models of B-cell malignancies
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Enrollment ongoing in phase II study of PHA-022121
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Nociceptive neurons shown to boost hematopoiesis
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Geron initiates phase III study of imetelstat in myelofibrosis refractory to JAK inhibitors
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ZyCoV-D vaccine candidate demonstrates safety and immunogenicity in phase I/II study
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Primary endpoint not met in phase III trial of eprenetapopt in TP53-mutant myelodysplastic syndromes
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