BioWorld Science

Jan. 18, 2021

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Discovery and characterization of specific inhibitors of human mitochondrial transcription

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Cellular underpinnings of allergen immunotherapy success

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F8-4-1BBL, a novel antibody-cytokine fusion protein with potent antitumor activity in vivo

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Presenilin mutations affect neuronal stem cells

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New causal gene for chronic kidney disease

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Trying to stay ahead of SARS-CoV-2 as variants emerge

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Overactive immunity can increase susceptibility to fungal infections

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With partner in crime, MYC repairs DNA breaks

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Interim data from phase II studies of novel combination immunotherapy in pancreatic cancer

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ViGeneron and Daiichi Sankyo collaborate to evaluate vgAAV for novel ophthalmic gene therapy

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FDA approves Enhertu for previously treated HER2-positive gastric or GEJ cancer

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CCS-1477, novel p300/CBP inhibitor with promising activity in prostate cancer

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Metrion and LifeArc extend neuroscience drug discovery collaboration

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Nanjing Sanhome Pharmaceutical patents PRMT5 inhibitors

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Dosing begins in phase IIa study of STP-705 for cutaneous basal cell carcinoma

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FDA approves Darzalex Faspro for newly diagnosed light-chain amyloidosis

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SinoMab initiates phase I trial in China with SN-1011 for autoimmune disease

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Novel anti-mesothelin and anti-FucGM1 ADCs show promising antitumor activity in vivo

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EdiGene obtains IND approval in China for ET-01 for transfusion dependent beta-thalassemia

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