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BioWorld Science

Jan. 18, 2021

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Discovery and characterization of specific inhibitors of human mitochondrial transcription

Cellular underpinnings of allergen immunotherapy success

F8-4-1BBL, a novel antibody-cytokine fusion protein with potent antitumor activity in vivo

Presenilin mutations affect neuronal stem cells

New causal gene for chronic kidney disease

Trying to stay ahead of SARS-CoV-2 as variants emerge

Overactive immunity can increase susceptibility to fungal infections

With partner in crime, MYC repairs DNA breaks

Interim data from phase II studies of novel combination immunotherapy in pancreatic cancer

ViGeneron and Daiichi Sankyo collaborate to evaluate vgAAV for novel ophthalmic gene therapy

FDA approves Enhertu for previously treated HER2-positive gastric or GEJ cancer

CCS-1477, novel p300/CBP inhibitor with promising activity in prostate cancer

Metrion and LifeArc extend neuroscience drug discovery collaboration

Nanjing Sanhome Pharmaceutical patents PRMT5 inhibitors

Dosing begins in phase IIa study of STP-705 for cutaneous basal cell carcinoma

FDA approves Darzalex Faspro for newly diagnosed light-chain amyloidosis

SinoMab initiates phase I trial in China with SN-1011 for autoimmune disease

Novel anti-mesothelin and anti-FucGM1 ADCs show promising antitumor activity in vivo

EdiGene obtains IND approval in China for ET-01 for transfusion dependent beta-thalassemia

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