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BioWorld Science

Feb. 18, 2021

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FDA accepts IND application for StroMel in osteoarthritis of knee

Ultra-low dose infection yields more accurate mouse model of tuberculosis

FDA approves IND for Signature Cord Prime in symptomatic knee osteoarthritis

A regulator of ER proteostasis shows promising antiviral activity against dengue and Zika viruses

New HSP90-CDC37 protein-protein interaction inhibitors with antitumor in vitro and in vivo efficacy

IMU-838 shows some evidence of clinical activity in CALVID-1 study in moderate COVID-19

Nektar announces new collaborations for registrational study of bempegaldesleukin in SCCHN

Topline data from phase Ib study of AMG-0103 in chronic discogenic low back pain

New ENPP2 inhibitors identified at Boehringer Ingelheim

AstraZeneca discovers arginase-1 and arginase-2 inhibitors

University of Texas, Axxam patent CX3CR1 and/or CX3CL1 agonists

Sichuan Haisco Pharmaceutical identifies kappa-opioid receptor agonist derivatives

New anoctamin-1 potentiators synthesized at Enterprise Therapeutics

First patient dosed in phase I study of IkT-148009

Highly phosphorylated GCase M-011 exhibits improved potential in Gaucher disease

N-803 plus BCG shows promise for treating NMIBC

First patient dosed in U.S. phase II/III COVID-19 outpatient study of RHB-107

AbFero receives funding for development of SP-420 for Parkinson's disease

Study may yield ways to harness bacterial antibiotic production

SciSparc signs agreement for phase IIa trial of SCI-110 for Alzheimer agitation

vTv initiates phase I study of PDE4 inhibitor HPP-737 for psoriasis

ABO-102 demonstrates evidence of clinical benefit in patients with MPS IIIA

U.K. clearance for first-in-human study of Avacta's FAP-activated doxorubicin prodrug AVA-6000

GSK initiates phase III program with RSV vaccine candidate GSK-3844766A for older adults

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