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BioWorld Science

March 9, 2021

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Chimerix opens enrollment in phase III study of dociparstat for AML

Macrophages dampen neuropathic pain

Collagen means well in pancreatic cancer

China's NMPA clears initiation of phase III trial of socazolimab for ES-SCLC

MacroGenics opens enrollment in phase II study of enoblituzumab in SCCHN

POPLAR study of imsidolimab in palmoplantar pustulosis does not meet primary endpoint

SBI and University of Oxford initiate phase II study of cardioprotective agent using 5-ALA

FDA clears IND for UX-053 for treatment of glycogen storage disease type III

Health Canada approves Estelle as first native estrogen-based combined oral contraceptive

Injecting sRNAs from the putamen of HD patients reproduces associated neuropathology in mice

Idorsia Pharmaceuticals patents LGALS3 inhibitors

Artios Pharma divulges POLQ inhibitors

Chinese investigators identify new TGFBR1 inhibitors

KalVista Pharmaceuticals presents KLKB1 inhibitors

Ivermectin does not significantly improve the time to resolution of symptoms in mild COVID-19

Clene Nanomedicine updates on clinical studies of CNM-Au8 gold nanocrystals

Bayer and DKFZ patent AhR antagonists

IL-17 receptor's "B team" may be pancreatic cancer target

Cell-based aHyC vaccine shows promise for treating patients with CRPC

Phase III CANOPY-2 trial of canakinumab in locally advanced or metastatic NSCLC misses OS endpoint

ASC-40 reduces liver fat in phase II China cohort in NASH

Xenon collaborates with Mount Sinai on phase II study of XEN-1101 for MDD and anhedonia

FDA clears IND for pivotal study of KN-046 for thymic carcinoma

AEON initiates phase II study of ABP-450 for preventive treatment of migraine

New model for invasive lobular carcinoma points to LOXL1 as a therapeutic target

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