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BioWorld Science

March 25, 2021

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Identification and preclinical evaluation of new gamma-secretase modulators to prevent and treat AD

Brain cell alcohol metabolism affects behavior, addiction

SF-1 antagonist OR-449 for treating ACC

Actinium and MSK evaluate Iomab-ACT for targeted conditioning prior to CD19 CAR T-cell therapy

Ferro Therapeutics synthesizes new PHGPx inhibitors

HiberCell identifies PERK inhibitors

Sunshine Lake Pharma presents new TR-beta agonists

Polivy approved in Japan for relapsed or refractory DLBCL

Chinese investigators patent TRK inhibitors

Kochi University discovers new KHSRP inhibitors

Japanese approval of additional indication for Riona

Seikagaku obtains approval in Japan for Joyclu intra-articular injection

Vitrakvi approved in Japan for NTRK fusion-positive advanced or recurrent solid tumors

Vidaza receives extended approval in Japan for acute myeloid leukemia

Uplizna gains Japanese approval for the treatment of neuromyelitis optica spectrum disorder

Corectim Ointment 0.25% and 0.5% approved in Japan as treatment of pediatric atopic dermatitis

Treakisym in combination with rituximab approved in Japan as treatment of R/R DLBCL

Microvesicles promote infarct recovery in primates

Guerbet reports positive phase III data for gadopiclenol

AstraZeneca reports primary analysis of U.S. phase III trial of AZD-1222

First patient dosed in phase I study of TH-1902 as treatment of sortilin-positive solid tumors

Synlogic achieves proof of mechanism for SYNB-8802 in dietary hyperoxaluria study

Positive topline data from phase II study of NurOwn as treatment of progressive MS

Phase II/III study of relatlimab with nivolumab in melanoma meets PFS primary endpoint

KM Biologics reports phase I data on tetravalent dengue vaccine KD-382

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