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BioWorld Science

March 29, 2021

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PepGen develops enhanced delivery oligonucleotides for muscular dystrophy

Albireo initiates dosing in key clinical studies with two of its candidates

Phase I study of intranasal adenovirus vector COVID-19 vaccine candidate, BBV-154

Cholesterol-independent heart disease risk gene

Ultrarare variants give insights into schizophrenia

T-cell 'auto-aggression' causes liver damage in NASH

Engineered myeloid cells prevent pro-metastatic microenvironments

Israeli startup goes bio(me)-prospecting in wild animals

University of Oxford to launch a phase I study evaluating nasally administered ChAdOx1 nCoV-19

Intensity Therapeutics to conduct phase II study of INT230-6 in early-stage breast cancer

AHR as novel therapeutic target for polycystic ovary syndrome

CC-90011 plus EP/EC shows safety in first-line extensive-stage SCLC

LINC00926 identified as a prognostic marker in lung adenocarcinoma

Foresee begins phase II/III study of FP-025 in COVID-19-associated ARDS

Phase II/III study of arimoclomol in inclusion body myositis misses endpoints

Researchers develop a Cyp17-overexpressing murine model of PCOS

Universtiy of Zurich, ETHZ patent bispecific binding agents targeting CD117 and CD3

HMPL-306 enters international phase I studies in solid tumors and hematological malignancies

Jiangsu Chia Tai Tianqing Pharmaceutical Group and collaborators describe GTPase KRAS inhibitors

Shanghai Institute of Materia Medica identifies new AXL and/or MET inhibitors

New ATX inhibitors identified by Humanwell Healthcare, collaborators

Phase IIb/III study of Zyesami for respiratory failure in critical COVID-19 meets primary endpoint

Wigen Biomedicine Technology discovers Wee1hu inhibitors

FDA approves Abecma for relapsed or refractory multiple myeloma

Phase Ib interim data on CDX-0159 for antihistamine-refractory chronic inducible urticaria

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