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Home » Newsletters » BioWorld Science

BioWorld Science

April 14, 2021

View Archived Issues

Human cerebral organoids show utility to evaluate candidate inhibitors of prion accumulation in CJD

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Phase III GOBI study of NOV-03 meets statistical significance on coprimary and secondary endpoints

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BMC-128 shows promising antitumor activity in mouse model of melanoma

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Phase II study of fostamatinib in patients with COVID-19 meets primary endpoint

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FDA clears IND application for phase IIb study of AXA-1125 in NASH

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Companies report progress of catumaxomab clinical trials for NMIBC

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CFT-7455 shows potent tumor regression in IMiD-resistant multiple myeloma xenografts

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First-in-class pan-inhibitor of KDM4 TACH-101 active in multiple cancer models

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SPH Biotherapeutics presents new isolated antigen-binding proteins

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New PARG inhibitors identified at Ideaya Biosciences

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Accutar Biotechnology synthesizes new androgen receptor degrading PROTACs

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Merck & Co. presents a novel potent, selective and brain-penetrant LRRK2 kinase inhibitor

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Merck & Co. discovers KRAS G12C mutant inhibitors

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BIAL Biotech discovers acid ceramidase inhibitors

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BNT-162b2 and mRNA-1273 achieve only partial cross-neutralization of novel SARS-CoV-2 variants

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Longeveron reports final phase I data on Lomecel-B in Alzheimer's disease

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Development of human African trypanosomiasis carbazole drugs

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New agonist MAb resolves chronic inflammation

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New phase II trials evaluate BI-456906 in obesity and NASH

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Tilt and MSD agree to study TILT-123 with Keytruda in ovarian cancer

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Bispecific antibody targeting LAG-3 and PD-L1 (ABL501) for cancer immunotherapy

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Iterion completes enrollment in phase I/IIa dose-expansion study of tegavivint in desmoid tumors

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Moderna updates progress of COVID-19 vaccine program

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Apellis reports 24-month data from phase Ib study of pegcetacoplan in geographic atrophy

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Trodelvy gains accelerated approval in U.S. for advanced urothelial cancer

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