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BioWorld - Monday, March 16, 2026
Home » Newsletters » BioWorld Science

BioWorld Science

April 23, 2021

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CVL-231 safe in healthy volunteers; evaluation in schizophrenia patients ongoing

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Studies reveal activity, mechanism of TAM kinase inhibitor PF-5807

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Phase III study finds Xywav improves excessive daytime sleepiness

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Observational study confirms good tolerability and efficacy of Intratect

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Second pivotal study of IDP-126 achieves all coprimary endpoints with statistical significance

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First patient dosed in investigator-initiated study of rigosertib in RDEB-associated SCC

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Monopteros initiates phase I/Ib study of MPT-0118 in solid tumors

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Phase III JUPITER-06 study of toripalimab plus chemotherapy meets primary endpoints

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Medshine Discovery divulges PD-1/PD-L1 interaction inhibitors

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Chinese investigators disclose HGFR and/or SRC and/or CSF1R inhibitors

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Roche presents HBsAg secretion inhibitors

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Alladapt initiates phase I/II Harmony Study of ADP-101

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Shanghai Litedd identifies new ROR-gammaT agonists

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Tolremo Therapeutics describes new DYRK1B inhibitors

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Phase II trial of selective oral DHODH modulator vidofludimus in RRMS

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FDA grants accelerated approval to Jemperli for dMMR endometrial cancer

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ProtoKinetix resumes phase I trials of PKX-001-treated islet cells in patients with type 1 diabetes

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ICAM-1 orchestrates radiotherapy abscopal effect

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Discovery of JBI-1527, small molecule inhibitor of PD-L1/PD-1 interaction

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OR-2805: a novel antibody targeting CD163 for the treatment of lung cancers

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Zenith agrees with Astellas to study ZEN-3694 with enzalutamide in metastatic CRPC

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