Home » Newsletters » BioWorld Science

BioWorld Science

April 23, 2021

View Archived Issues

CVL-231 safe in healthy volunteers; evaluation in schizophrenia patients ongoing

Studies reveal activity, mechanism of TAM kinase inhibitor PF-5807

Phase III study finds Xywav improves excessive daytime sleepiness

Observational study confirms good tolerability and efficacy of Intratect

Second pivotal study of IDP-126 achieves all coprimary endpoints with statistical significance

First patient dosed in investigator-initiated study of rigosertib in RDEB-associated SCC

Monopteros initiates phase I/Ib study of MPT-0118 in solid tumors

Phase III JUPITER-06 study of toripalimab plus chemotherapy meets primary endpoints

Medshine Discovery divulges PD-1/PD-L1 interaction inhibitors

Chinese investigators disclose HGFR and/or SRC and/or CSF1R inhibitors

Roche presents HBsAg secretion inhibitors

Alladapt initiates phase I/II Harmony Study of ADP-101

Shanghai Litedd identifies new ROR-gammaT agonists

Tolremo Therapeutics describes new DYRK1B inhibitors

Phase II trial of selective oral DHODH modulator vidofludimus in RRMS

FDA grants accelerated approval to Jemperli for dMMR endometrial cancer

ProtoKinetix resumes phase I trials of PKX-001-treated islet cells in patients with type 1 diabetes

ICAM-1 orchestrates radiotherapy abscopal effect

Discovery of JBI-1527, small molecule inhibitor of PD-L1/PD-1 interaction

OR-2805: a novel antibody targeting CD163 for the treatment of lung cancers

Zenith agrees with Astellas to study ZEN-3694 with enzalutamide in metastatic CRPC

Popular Stories

Today's news in brief
BioWorld
SCAN is core circuit affected in Parkinson’s disease
BioWorld Science
Parkinson’s disease (PD) is a neurodegenerative disorder that affects movement, and tremor is one of its signatures. But it is a much more wide-ranging disorder,...
TL1A is overexpressed in hidradenitis suppurativa
BioWorld Science
Despite the availability of advanced therapeutic options, about 40%-50% of patients with hidradenitis suppurativa do not achieve significant improvement in...
Astellas’ ASP-2246 shows promise in stroke management
BioWorld Science
Astellas Pharma Inc. recently presented data regarding ASP-2246, a drug candidate comprised of an mRNA encoding the transcription factor NeuroD1 encapsulated in...
IL-22 and TL1A, a robust couple for diagnosing hidradenitis suppurativa
BioWorld Science
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease with strong association with psoriasis and inflammatory bowel disease (IBD). While some...