BioWorld Science

May 26, 2021

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NCX-667 demonstrates IOP-lowering ability in a number of animal models

Targeting senescent cells restores kidney function

Boehringer Ingelheim accepts DCR-LIV2 as development candidate under Dicerna agreement

Aptorum advances ALS-4 and SACT-1 programs

Vacdiagn Biotechnology patents recombinant viral vector encoding tumor antigens

NanoCarrier describes shRNA/siRNA targeting mutant COL3A1

First data for AJM-347 shows promise for the treatment of IBD

EA Pharma has presented the pharmacological characterization of the company's oral alpha4beta7 integrin antagonist AJM-347, in development as a treatment for inflammatory bowel disease (IBD). Read More

Preclinical data support clinical evaluation of iOnctura's autotaxin inhibitor IOA-289

Recursion initiates IND-enabling studies of its novel small molecule toxin inhibitor

Data reported from CRPC cohort 6 of COSMIC-021 study of cabozantinib plus atezolizumab

NextCell Pharma initiates phase I study of ProTrans in patients with COVID-19

GR antagonist CORT-125329 shows selectivity and activity in vitro and in vivo

Janssen Biotech discloses new dihydroorotate dehydrogenase inhibitors

New PARP-1 inhibitors described by Kukje Pharma, Chungnam National University

New CD38 inhibitors discovered at Mitobridge

Xilio and Merck & Co. collaborate on anti-CTLA-4 MAb program

Moleculin receives clearance to initiate phase Ib/II study of annamycin for STS lung metastases

Phase I data presented for MEDI-6570 in patients with T2DM

Sonelokimab shows significant clinical benefit over placebo in patients with plaque psoriasis

Results published from trial evaluating a therapeutic based on equine polyclonal Abs for COVID-19

Sparrow Pharmaceuticals presents new data on SPI-62 for Cushing's syndrome

Spruce Biosciences reports phase IIa data on tildacerfont in classic congenital adrenal hyperplasia

FDA places clinical hold on Larimar's CTI-1601 for Friedreich's ataxia

FDA approves IND for NBL-015 anti-Claudin 18.2 antibody

Connect begins phase I trial of CBP-174 for chronic inflammatory pruritus

Abivax reports phase IIb data on ABX-464 in moderate to severe ulcerative colitis

Today's news in brief

BioWorld

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BioWorld MedTech

BioWorld MedTech briefs for Dec. 5, 2025.

Hippocratic loath? ‘Harm’ threat from ACIP’s proposed HBV shift

BioWorld

Individual liberty and choice vs. wider public health became one predictable hinge upon which swung the often-acerbic debates at the CDC’s Advisory Committee for...

Høeg appointment as acting CDER director tied to vaccine strategy?

BioWorld

After a more than 13-year period of stability with Janet Woodcock as the head of CDER, with Patrizia Cavazzoni taking charge during the next four years of former...

Illustration of chromosome unraveling down to the DNA

First phase of synthetic human genome project successfully completes

BioWorld

The first phase of the U.K. synthetic human genome project has successfully completed, realizing key steps in chromosome synthesis. The work has demonstrated a...