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BioWorld - Monday, December 8, 2025
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BioWorld Science
June 8, 2021
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First-in-human data for GS-5718 shows drug is safe and well tolerated
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SYHX-1901 enters phase I trial in healthy Chinese subjects
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Phase I trial evaluates GNC-039 in relapsed/refractory or metastatic solid tumors
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Results presented from FIH study of RBN-2397 in patients with advanced solid tumors
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Chengdu Baiyu Pharmaceutical divulges NLRP3 inflammasome inhibitors
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New ERAP1 inhibitors identified at Grey Wolf Therapeutics
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Roche discovers Toll-like receptor 7/8/9 antagonists
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Sichuan Haisco Pharmaceutical patents G12C mutant KRAS inhibitors
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New N-acetyl-beta-D-glucosaminidase inhibitors identified at Janssen
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IGF-1Ec expression increased in advanced papillary thyroid carcinoma
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Responses seen with BDB-001 plus pembrolizumab in patients with advanced solid tumors
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First subject dosed in phase I study of fibrosis candidate RXC-007
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Enrollment begins in phase II study of paxalisib in primary CNS lymphoma
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StemVacs-V iPSC amplifies cancer-specific immune response and shows synergy with other therapies
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First patient dosed in phase II study of CRS-3123 to treat Clostridioides difficile infection
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Selpercatinib shows promising safety and efficacy in RET-altered solid tumors in pediatric patients
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FDA lifts clinical hold on studies of LentiGlobin in sickle cell disease and beta-thalassemia
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MERS coronavirus study gives insights into zoonotic potential
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Brentuximab vedotin meets the primary endpoint in diffuse cutaneous systemic sclerosis study
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China's NMPA approves clinical trial application for second indication of CT-120
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Preliminary phase I data for ST-266 in glaucoma suspect patients
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FDA clears IND for CLN-049 bispecific antibody for relapsed/refractory AML
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MediciNova initiates sheep study to develop MN-166 as treatment for chlorine gas-induced lung injury
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Iksuda completes financing round to support progression of ADCs
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