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BioWorld - Thursday, December 11, 2025
Home » Newsletters » BioWorld Science

BioWorld Science

June 15, 2021

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Phase I trial shows diagnostic potential of 64Cu-SAR-bombesin PET/CT in patients with breast cancer

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New mouse model recapitulates the pancreatic features of human MODY5

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First patient dosed in phase I/II study of CFT-7455 in hematologic malignancies

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Positive topline data from phase IIa LIFT study of TERN-101 in NASH

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Sirtuin affects cardiac lipotoxicity via secondary mechanism

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Celastrol-loaded NPs induce selective apoptosis of macrophages and osteoclasts in arthritic joints

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IL1RAP is a key driver of metastasis and a potential immunotherapy target in Ewing sarcoma

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Janssen Pharmaceutica discloses new Mcl-1 inhibitors

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SIRT6 is a potential therapeutic target to preserve healthy aging and delay the onset of frailty

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Suven Life Sciences patents prodrugs of abiraterone for cancer

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Senda Biosciences identifies new AhR antagonists

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Roche synthesizes muscarinic M4 receptor PAMs

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University of Utah divulges TRPV4 antagonists

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First-in-human data presented for the anti-CD47 MAb AK-117

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BT-200: prolonging half-life of vWF

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YL-13027 demonstrates safety and preliminary activity in patients with solid tumors

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Topline phase Ib data reported on RPT-193 in atopic dermatitis

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Cocrystal's CDI-45205 shows in vitro activity against SARS-CoV-2 and variants

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Novadip reports phase I data on first-generation autologous cell-based osteogenic product NVD-001

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Exelixis and Bristol Myers Squibb agree to study XL-092 with immuno-oncology therapies

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G1 Therapeutics initiates phase II trial of Cosela in metastatic bladder cancer

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FDA clears IND for lisaftoclax for ER-positive breast cancer and other solid tumors

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Mindset reports first preclinical psychedelic benchmark data from COPE program

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EyeGate begins phase II proof-of-concept study of PP-001 for ocular surface inflammation

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XWPharma reports phase I data on XW-10172 for sleep disorders

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