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BioWorld Science

June 18, 2021

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PureTech advances its wholly owned pipeline

Phase II results presented for ZYN-002 in children and adolescents with DEE

BriaCell advances personalized immunotherapies for prostate cancer, melanoma and lung cancer

FDA accepts IND for phase I trial of Xilio's XTX-101 in solid tumors

Algernon plans phase I study of AP-188 for stroke

Akaal reports preclinical data on AK-119 in neuropathic pain

Modus collaborates with Imperial College London on clinical study of sevuparin in malaria

Harbour BioMed begins phase I dosing with HBM-4003 in NSCLC

Satsuma reports phase I safety and PK data on STS-101

4SC and NKI collaborate to study neoadjuvant domatinostat in urothelial carcinoma

Amgen synthesizes new fatty acid desaturase 1 inhibitors

Daewoong Pharmaceutical patents JAK3 inhibitors

Aurigene Discovery Technologies presents new CD73 inhibitors

Chinese investigators describe new JAK inhibitors

Alnylam Pharmaceuticals divulges ATXN3-targeting ds-siRNAs

Phase I data for the novel first-in-class anti-SIRPalpha antibody, BI-765063

177Lu-DOTAGA.(SA.FAPi)2 use for thyroid cancer

Viking reports phase I data on TRbeta agonist VK-0214

New basket trial evaluates spartalizumab in tumors with high PD-1 expression levels

Reversible BTK inhibitors from Hyperway described

HSV-targeting compound affects latent infection

Anji licenses rights to MCL1 inhibitor program from Broad Institute

Histopathology data reported for TATX-03a in SARS-CoV-2 challenged hamsters

Kite and ShoreLine Biosciences partner on allogeneic cell therapies for hematologic malignancies

Qpex opens phase I study of QPX-9003 for infections caused by drug-resistant Gram-negative pathogens

Evaluation of DAN-222 alone or in combination with PARP inhibitor in models of breast cancer

Increased PARP activity in PBLs could predict prostate cancer susceptibility

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