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BioWorld Science

June 29, 2021

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OPS-2071 shows potent in vitro and in vivo activity against Clostridioides difficile

New Raf kinase C inhibitors identified at Medshine Discovery

Cadila Healthcare discovers NLRP3 inflammasome inhibitors

Kallyope describes new SSTR5 antagonists

New PRMT5 inhibitors discovered at Lupin

First-in-human study finds CEB-01 implant safe in patients with retroperitoneal soft tissue sarcoma

TAT therapy with FPI-1792 plus checkpoint inhibitors eradicates colon cancer tumors in vivo

Second ANAVEX2-73 trial confirms SIGMAR1 mRNA expression as predictive biomarker of response

Topline phase I data presented for DARE-HRT1 for hormonal therapy after menopause

Genetic study unveils loss-of-function variants in BCAS3 causing a neurodevelopmental disorder

RNA helicase DDX3X identified as an attractive target for host-directed therapy against SARS-CoV-2

Ideaya provides clinical updates for IDE-397 phase I study and darovasertib combination trial

First patient dosed in phase I/II study of ANV-419 in solid tumors

Umbilical cord-derived mesenchymal stem cells show clinical efficacy in patients with COVID-19

FDA clears IND application for ORIC-533

Interim data from phase II CORIST study of SCO-101 in metastatic colorectal cancer

LDL receptor overexpression affects tauopathy in Alzheimer's model

Venatorx initiates phase I trial of VNRX-9945 for chronic hepatitis B

Human placenta-derived exosomes for the treatment of ischemia

Q-State reports preclinical proof-of-concept data for QSB-490 in spastic paraplegia type 49

First-in-human data for SCO-267 in healthy adults and subjects with glucose intolerance

SAB Biotherapeutics initiates phase IIa trial of SAB-176 for influenza

DiaMedica reports interim phase II data on DM-199 in chronic kidney disease

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