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BioWorld - Saturday, December 6, 2025
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BioWorld Science
June 25, 2021
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Wuhan LL Science and Technology Development Co. patents P2X4 receptor antagonists
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New GTPase KRAS inhibitors discovered at REVOLUTION Medicines
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Kyorin Pharmaceutical and collaborators describe protein G9a inhibitors
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Sinovent identifies new GTPase KRAS G12C mutant inhibitors
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New CDK8 and/or CDK19 inhibitors synthesized at the Dana-Farber Cancer Institute
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Karuna reports phase Ib data on KarXT in healthy elderly volunteers
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XBiotech initiates trial of XB-2001 with chemotherapy for pancreatic cancer
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First-in-human study of BDB-018 explores use in advanced solid tumors
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Seal Rock begins phase I trial of SRT-015 for NASH
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Titan reports in vivo data on TP-2021 implant in model of chronic pruritus
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Mercaptor advances programs in COVID-19 brain inflammation and epilepsy
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Study supports miR panel for diagnosing multiple sclerosis
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CStone reports data on Gavreto in Chinese patients with advanced RET fusion-positive NSCLC
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Fulcrum reports phase IIb data on losmapimod in FSHD
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Sellas reports phase I data on galinpepimut-S with nivolumab in malignant pleural mesothelioma
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Kaken begins Japanese phase I study of sofpironium bromide gel in primary palmoplantar hyperhidrosis
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Back to the basics for new insights, with new technology
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Applied Genetic Technologies reports 12-month data from phase I/II achromatopsia trials
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Follicum discontinues development of FOL-005 for alopecia
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Aravive advances phase Ib evaluation of AVB-500 with cabozantinib in clear cell renal cel carcinoma
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Arcus provides interim analysis from ARC-7 study of domvanalimab combinations in NSCLC
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Dosing begins in phase II study of ALPN-101 in SLE
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First patient enters phase II study of TG-4001 with avelumab in HPV16-positive anogenital tumors
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IN3BIO cleared to begin phase I/II trial of IN-01 for colorectal cancer in Bulgaria
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Abivax reports phase IIa data on ABX-464 in rheumatoid arthritis
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SelectImmune Pharma and Lonza collaborate to develop processes for novel immunotherapy protein NlpD
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Carmot opens phase I study of dual GLP-1 and GIP receptor modulator CT-388
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Bristol Myers Squibb exercises option to U.S. license for Prothena's PRX-005
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4D Molecular Therapeutics reports pipeline update
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