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BioWorld - Friday, December 5, 2025
Home » Newsletters » BioWorld Science

BioWorld Science

July 6, 2021

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Enrollment ongoing in phase I/II study of PVSRIPO

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Mersana starts phase I/II umbrella study of XMT-1536 in high-grade serous ovarian cancer

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Venadaparib shows safety and preliminary efficacy in first-in-human trial

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Novel tau tubulin kinase 1 inhibitors reduce tau phosphorylation in vivo

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Vaccinia virus-expressed SARS-CoV-2 spike protein promotes cellular and humoral immunity in mice

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Antitumor activity of luxeptinib described in phase Ia/b study in B-cell malignancies

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BCMA CAR-T cells engineered with membrane-bound IL-15 show increased in vivo activity

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Dose-dependent weight loss seen in first-in-human study of LY-3437943

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Model of diastolic dysfunction with preserved ejection fraction developed to test HDAC6 inhibition

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Phase I data for CC-90001 in healthy subjects and in participants with hepatic impairment

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Roche patents new BRAF inhibitors

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Chinese investigators divulge P2X3 receptor antagonists

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Shenzhen Jingtai Technology presents Ret inhibitors

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Vivavision Biotechnology describes new ROCK2 inhibitors

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PTC Therapeutics discloses compounds for familial dysautonomia

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SYNB-1934, optimized live bacterial therapeutic for the treatment of phenylketonuria

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Bio-ADM, a novel biomarker of congestion in acute dyspnea

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Phase II FORCE study of avdoralimab in COVID-19 misses primary endpoints

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Phase I/II trial explores Gadeta's gamma delta TCR cell therapy GDT-002 for multiple myeloma

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Downregulation of ERBB4 leads to peripartum cardiomyopathy

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HUTCHMED initiates phase I study of HMPL-295 in advanced solid tumors

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HIV rebound biomarkers give insights into controllers and, unexpectedly, comorbidities

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BNC-210 advances into phase IIb trial in PTSD

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