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BioWorld - Sunday, April 26, 2026
Home » Newsletters » BioWorld Science

BioWorld Science

July 7, 2021

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Aston Sci studies AST-021p for advanced solid tumors in phase I

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DIO2 is a regulator of mitochondrial activity in developing human cardiomyocytes

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TruLarv standardized Galleria mellonella developed for screening new antimicrobials

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New beta-amyloid PET imaging agent [18F]Flotaza shows promise in Alzheimer's disease brain

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Positive interim data from phase Ib study of ARO-HIF2 in clear cell renal cell carcinoma

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First patient dosed in phase IIb study of Lomecel-B in hypoplastic left heart syndrome

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Positive phase I data for UBX-1325 in patients with advanced vascular eye disease

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FDA clears IND for AGEN-1777

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Vanderbilt University patents muscarinic M4 receptor antagonists

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Shionogi discloses new HDAC2 inhibitors

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Kymera Therapeutics patents new PROTACs

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Eli Lilly and Company synthesizes GTPase KRAS mutant inhibitors

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Ifenprodil will not advance into phase III trial for COVID-19

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Intra-Cellular Therapies identifies new gamma-carboline derivatives

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NMPA accepts IND application for TST-002 anti-sclerostin monoclonal antibody

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SYNB-8802 significantly lowers urinary oxalate in NHP model of hyperoxaluria

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Dapagliflozin similarly reduces risk of worsening in Black and White patients with HFrEF

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Adamtsl3 knockout leads to dilated cardiomyopathy in aortic banded mice

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APOBEC3B may be a therapeutic target for treating ovarian cancer

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Studies report on developmental, adult neurogenesis

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NextCure's NC-762 enters phase I/II trial in advanced or metastatic solid tumors

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Opiant reports topline data from confirmatory PK study of OPNT-003 for opioid overdose

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FDA clears initiation of phase II trials of YH-001 and YH-003 in advanced cancers

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Sorrento cleared in U.S. to begin phase II study of resiniferatoxin in knee osteoarthritis pain

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EpimAb Biotherapeutics commences dosing in phase I/II trials of EMB-06 and EMB-02

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