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BioWorld - Thursday, March 28, 2024
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BioWorld Science
July 7, 2021
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Aston Sci studies AST-021p for advanced solid tumors in phase I
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DIO2 is a regulator of mitochondrial activity in developing human cardiomyocytes
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TruLarv standardized Galleria mellonella developed for screening new antimicrobials
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New beta-amyloid PET imaging agent [18F]Flotaza shows promise in Alzheimer's disease brain
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Positive interim data from phase Ib study of ARO-HIF2 in clear cell renal cell carcinoma
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First patient dosed in phase IIb study of Lomecel-B in hypoplastic left heart syndrome
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Positive phase I data for UBX-1325 in patients with advanced vascular eye disease
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FDA clears IND for AGEN-1777
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Vanderbilt University patents muscarinic M4 receptor antagonists
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Shionogi discloses new HDAC2 inhibitors
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Kymera Therapeutics patents new PROTACs
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Eli Lilly and Company synthesizes GTPase KRAS mutant inhibitors
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Ifenprodil will not advance into phase III trial for COVID-19
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Intra-Cellular Therapies identifies new gamma-carboline derivatives
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NMPA accepts IND application for TST-002 anti-sclerostin monoclonal antibody
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SYNB-8802 significantly lowers urinary oxalate in NHP model of hyperoxaluria
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Dapagliflozin similarly reduces risk of worsening in Black and White patients with HFrEF
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Adamtsl3 knockout leads to dilated cardiomyopathy in aortic banded mice
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APOBEC3B may be a therapeutic target for treating ovarian cancer
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Studies report on developmental, adult neurogenesis
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NextCure's NC-762 enters phase I/II trial in advanced or metastatic solid tumors
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Opiant reports topline data from confirmatory PK study of OPNT-003 for opioid overdose
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FDA clears initiation of phase II trials of YH-001 and YH-003 in advanced cancers
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Sorrento cleared in U.S. to begin phase II study of resiniferatoxin in knee osteoarthritis pain
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EpimAb Biotherapeutics commences dosing in phase I/II trials of EMB-06 and EMB-02
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