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BioWorld Science

July 19, 2021

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HER2 CAR-NK cells show preclinical antitumor activity without off-target cytotoxicity

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TGF-beta-mediated mTOR inhibition preserves cellular metabolism of precursors of exhausted T cells

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New prosthetic valvular graft infection model shows benefit of adjunctive fibrinolytic treatment

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Model of steroid-resistant neutrophilic asthma developed to test treatments

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GFAP a biomarker in frontotemporal lobar degeneration and primary psychiatric disorders

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TYK Medicines divulges new Ret inhibitors

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Wigen Biomedicine Technology presents KRAS mutant inhibitors

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FDA accepts IND application for phase IIa study of Quilience as treatment of narcolepsy

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UCB discloses new FCER1A mutant inhibitors

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FDA clears IND for phase I trial of SYSA-1801 in advanced pancreatic cancer

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Phase I trial investigates SHJ-002 for myopia in pediatric subjects

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ABBV-CLS-7262 studied in phase I for ALS

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BIX-119 leads to improved clinical benefit through blocking both IL-17 and IL-22

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Scioto opens phase I study of SB-121 in participants with autistic disorder

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New neonatal murine model of Listeria monocytogenes meningitis developed

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Clarity recruits patients with prostate cancer to evaluate PET imaging with [64Cu]SAR-bisPSMA

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Discovery of novel selective Axl inhibitor with antitumor activity in vivo

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Phase II/III trial studies SHR-1701 with BP-102 and XELOX in first-line metastatic colorectal cancer

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U.S. phase II trial explores use of Velexbru in primary central nervous system lymphoma

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CytoDyn reports preliminary data on leronlimab in metastatic TNBC

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