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BioWorld Science

Aug. 3, 2021

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First patient dosed in phase II study of ZN-c3 in uterine serous carcinoma

Vaxart's IND application for S-only oral tablet COVID-19 vaccine cleared in U.S.

Hovione Scientia describes ligand drug conjugates including BET inhibitors

Bristol Myers Squibb patents CD80/PD-L1 and/or PD-1/PD-L1 interaction inhibitors

New CDK and TRK inhibitors identified at Hangzhou Innogate Pharma

Ascentage Pharma discovers mutant GTPase KRAS inhibitors

FDA clears IND for phase I/II MARINA study of AOC-1001

Dosing begins in phase I study of mRNA-6231

Prometheus initiates phase IIa APOLLO-CD study of PRA-023 in Crohn's disease

Discovery of SR-42667: a tau-SH3 interaction inhibitor that prevents Abeta toxicity

Phase II data show safety and efficacy of OCS-02 in dry eye disease

Gem gene sparkles as ischemic stroke drug discovery target

China's NMPA approves INDs for IASO's CD19/CD22 CAR-T therapy

Collagenase clostridium histolyticum improves foot function in plantar fibromatosis study

Abcentra studies orticumab in subjects with psoriasis and cardiometabolic risk factors

Intranasal vaccination with ChAdOx1 nCoV-19 reduces viral shedding in preclinical models

ST-067 enters first-in-human study in relapsed or refractory solid tumors

Phase I trial evaluates iPSC-derived CAR T-cell therapy FT-819 for CD19+ malignancies

Phase I data with ANG-3070 pave way for phase II study in primary proteinuric kidney diseases

CTA approved in Vietnam for phase I/II/III study of SARS-CoV-2 vaccine ARCT-154

Dosing underway in phase I/II study of KRAS G12C inhibitor JAB-21822

Annovis reports interim phase II data on Posiphen in Alzheimer's and Parkinson's disease

ACD-856 shows preclinical effects on cognition, enters phase I study

FDA authorizes IND for phase I testing of Sorrento's CD38 DAR-T cell therapy candidate

Luye Pharma files IND in U.S. to study next-generation VMAT2 inhibitor LY-03015

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