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BioWorld Science

Aug. 25, 2021

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Engineered ACE2 protects against SARS-CoV-2 infection in vivo

Lilly describes new GIPR and GLP-1 receptor agonists

New PTPN11 inhibitors identified at Medshine Discovery

Zhejiang Hisun Pharmaceutical patents TYK2/JAK-1/JAK-2/JAK-3 inhibitors

Incyte discovers GTPase KRAS mutant inhibitors

KalVista presents structure and preclinical data for pKA inhibitor KVD-001

New dual orexin receptor agonists for the treatment of orexin-deficient disorders such as narcolepsy

Study of MAPT-mutated cerebral organoids reveals mechanisms of glutamatergic cortical neuronal death

STING signaling identified as a therapeutic target for Niemann-Pick disease type C

FDA clears IND for phase II study of CardiolRx for acute myocarditis

Bio-Path receives IND clearance for phase I/Ib study of BP-1002 in relapsed or refractory AML

EOM initiates phase I/IIa study of EOM-613 in hospitalized COVID-19 patients

Stachydrine-leonurine conjugate SL-06 ameliorates experimental cerebral ischemic stroke

Ascletis completes bridging study and opens Chinese phase II trial of ASC-42 for chronic hepatitis B

Adjuvance reports interim phase I data on next-generation saponin adjuvant TQL-1055

Anti-CFH antibodies determine the outcome in primary membranous nephropathy

Serodus initiates phase II/III study of SER-150 in diabetic kidney disease

Phase II trial of roxadustat for chemotherapy-induced anemia meets primary efficacy endpoint

Ultragenyx opens enrollment in adaptive study of UX-701 in Wilson's disease

Moving side chains amps up peptides' infection-fighting abilities

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