BioWorld Science

Sep. 9, 2021

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Synthesis and optimization of LRRK2 inhibitors using a CHK1-derived crystallographic surrogate

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New MAP4K4 inhibitors identified for suppressing cardiac muscle cell death

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New sporadic Alzheimer's disease animal model may improve drug testing

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GABA-A alpha5 PAM RO-7015738 presented for neurological disorders

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Genfleet Therapeutics discovers RIP-1 inhibitors

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New IRAK-4/FLT-3 inhibitors identified at PharmaBlock Sciences

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Amgen describes new PRMT5 inhibitors

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New EGFR mutant inhibitors identified at Betta Pharmaceuticals

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New DNA vaccine shows promise against Ebola virus infection

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Microglial activation and tau spreading correlate with Braak stages in AD

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NIH develops PET radioligands targeting CSF-1R for neuroinflammation

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ProQR and Lilly to use Axiomer RNA editing platform to target liver and nervous system disorders

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Update from large animal pilot dosing study of BB-301 for oculopharyngeal muscular dystrophy

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mRNA-1273 vaccine induces antibodies against SARS-CoV-2 variants

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Herantis advances project to combine Nanoform's technology with rhCDNF for Parkinson's disease

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Reprogramming the tumor-immunosuppressive microenvironment to control metastasis

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Researchers give rationale on the development of RAF-selective MEK inhibitors for cancer

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Gut bacteria accumulate multiple therapeutic drugs

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PAQ and Insilico Medicine collaborate to develop therapies through autophagy-dependent degradation

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