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BioWorld Science

Oct. 13, 2021

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Potent selective pan-serotype dengue inhibitor developed

Discovery and preclinical characterization of novel TLR3 agonist, TL-532

Jiangsu Hengrui Medicine, Shanghai Hengrui Pharmaceutical patent ADCs including B7-H3 antibodies

New NLRP3 inflammasome inhibitors identified at Astellas Pharma

Atux Iskay presents new anticancer compounds

New TRK inhibitors divulged by J2H Biotech

Preclinical data presented for RP-3500

NVL-520 demonstrates efficacy in PDX models harboring ROS1 fusions

Regeneration of GABAergic neurons by in vivo reprogramming of glial cells reduces epileptic seizures

BRD9 is a druggable target for treating ccRCC with absent or low HIF-2alpha expression

ENPP1 inhibitor TXN-10128 shows promising antitumor activity trough restoration of STING activation

AavantiBio expands partnership with University of Florida to create gene therapy capsids

Creative Medical Technology announces proof-of-concept data on ImmCelz immunotherapy product

Hereditary Neuropathy Foundation and Rarebase partner to find treatments for Charcot-Marie Tooth

Poseida and Takeda partner on nonviral in vivo gene therapy programs

Amydis receives NINDS funding to explore presence of ASYN in retina of Parkinson's models

Kallistatin is a marker of NAFLD progression in patients with hypertension

NV-CoV-2 effective against SARS-CoV-2 in standard cell culture pseudovirion assay

Liver TR-beta1 activation can alleviate nonalcoholic steatohepatitis

NCI grant supports development of ST-316 to treat Wnt/beta-catenin-dependent breast cancer

Preclinical data support use of ibrexafungerp to treat mucormycosis

Emmaus gains license to Kainos' novel IRAK-4 inhibitor KM-10544

BridgeBio reports highlights from preclinical cancer and gene therapy pipelines

Vaxil reports data on P-Esbp-DOX in mouse model of aggressive liver metastasis of colorectal tumors