BioWorld Science

Nov. 25, 2021

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CDX-585, a novel bispecific antibody targeting ILT4 and PD-1 for cancer treatment

Adenosine A1R/A3R agonist AST-004 ameliorates brain infarction in an NHP model of stroke

Pfizer describes new MAP4K1 inhibitors

New Bcl-2 inhibitors discovered at Prelude Therapeutics

IL-17A/IL-17RA interaction modulators patented by Janssen Pharmaceutica

New PADI4 inhibitors synthesized at Gilead

Meiji Seika Pharma divulges histamine H4 receptor antagonists

Discovery of KSQ-004, a Regnase-1/SOCS1 dual-edited human CRISPR/Cas9-engineered TIL therapy

Anti-CLDN18.2 BiME ES-028 shows promise as cancer immunotherapeutic

Probiotic strategy prevents Enterococcus escape from the gut

"I was not always someone who would have advertised probiotics," Michael Otto told BioWorld Science. And it's easy to see why. At this point, probiotics are more often dubious wellness offerings than evidence-based therapeutics. Read More

XIAP deficiency is associated with susceptibility to microbial triggers of intestinal inflammation

PCC-0105002 attenuates neuropathic pain without motor coordination-associated side effects

Restoration of NXTAR as a novel approach for prostate cancer treatment with enzalutamide

Liver-humanized mice developed as more accurate model of human cardiometabolic diseases

Today's news in brief

BioWorld

BioWorld briefs for Dec. 24, 2025.

Today's news in brief

BioWorld MedTech

BioWorld MedTech briefs for Dec. 24, 2025.

Illustration of magnifying glass looking at cancer in the brain

Researchers discover how glioblastoma tumors dodge chemotherapy

BioWorld MedTech

Researchers at the University of Sydney have uncovered a mechanism that may explain why glioblastoma returns after treatment, and the world-first discovery offers...

Illustration of tau accumulating in a neuron cell.

ADEL wins $1.04B Sanofi deal for tau-targeting Alzheimer’s drug

BioWorld

ADEL Inc. closed a year-end licensing deal worth up to $1.04 billion with Sanofi SA for ADEL-Y01, a specific tau-targeting Alzheimer’s disease drug candidate in a...

Left: Anthony Fauci. Right: Transmission electron micrograph of HIV-1 virus particles

HIV research is close to a cure but far from ending the pandemic

BioWorld

Advances in antiretroviral therapy (ART) now allow people living with HIV to lead normal lives with undetectable and nontransmissible levels of the virus in their...