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BioWorld Science

Dec. 15, 2021

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Siglec-15 expression is increased in leukemia and its targeting may be promising for therapy

Oncolys BioPharma discloses new compounds against SARS-CoV-2 infection

Guangzhou Fermion Technology patents SST4 receptor agonists

New pancreatic cancer immune therapy target identified

Concert Pharmaceuticals presents new JAK inhibitors

Chinook Therapeutics identifies LDHA inhibitors

Genexine presents fusion proteins for treating immune diseases

Panbela's SBP-101 shows preclinical promise for ovarian cancer

BCL6 PROTAC degrader ARVN-71228 shows efficacy in preclinical models of DLBCL

ASP-8731 inhibits microvascular stasis in models of sickle cell disease

Preclinical data show specificity of Alzinova's ALZ-201 for toxic form of Abeta peptide

RALA as a potential therapeutic target in TNBC

CAN-10 shows promise in systemic sclerosis model

Generation Bio reports progress in hemophilia A program

CHK1 loss promotes the antiproliferative activity of ERK inhibitors in KRAS-mutant PDAC

PRMT5 targeting for the treatment of ER+/RB1-deficient breast cancer

ENSA negatively regulates NEP activity and may be a therapeutic target to lower amyloid beta

Targeting NSDHL could prevent breast cancer initiation and progression

In vitro data show reduction in neutralizing activity of ADG-20 against SARS-CoV-2 Omicron variant

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